SCHEMBL20735489

SCHEMBL20735489

Nc1c(N)c2c3ccccc3cc3ccc4cccc1c4c32

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.58
ERBB2 P04626 1/20 0.58
FYN P06241 1/20 0.58
MAOA P21397 1/20 0.58
ACHE P22303 1/20 0.58
AHR P35869 1/20 0.58
ALDH1A1 P00352 8/20 0.48
HSD17B10 Q99714 8/20 0.48
HPGD P15428 5/20 0.48
THRB P10828 1/20 0.48
NQO2 P16083 2/20 0.39
HIF1A Q16665 3/20 0.39
CYP1B1 Q16678 2/20 0.39
CES1 P23141 1/20 0.39
HTR2A P28223 1/20 0.38
NQO1 P15559 1/20 0.38
TSHR P16473 4/20 0.38
CYP3A4 P08684 3/20 0.38
KEAP1 Q14145 1/20 0.38
CASP1 P29466 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4855399 0.82 CYP1A2 (0.69) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL20735488 0.82 ALDH1A1 (0.62) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL29553771 0.82 ALDH1A1 (0.62) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL29876464 0.80 CYP1A2 (0.73) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL31019665 0.80 CYP1A2 (0.73) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL55923 0.80 CYP1A2 (0.73) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL5470699 0.80 CYP1A2 (0.64) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL4852473 0.79 CYP1A2 (0.64) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL20735490 0.78 CYP1A2 (0.63) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL4851973 0.77 CYP1A2 (0.74) CYP1A2ERBB2FYNMAOAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10995217-B2 Compounds as potential dye molecules Lleaf Pty Ltd (AU) 2021-05-04 US disclosed
US-20200199367-A1 COMPOUNDS AS POTENTIAL DYE MOLECULES Lleaf Pty Ltd (AU) 2020-06-25 US disclosed
WO-2019028508-A1 \"COMPOUNDS AS POTENTIAL DYE MOLECULES\ Lleaf Pty Ltd (AU) 2019-02-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200199367-A1 COMPOUNDS AS POTENTIAL DYE MOLECULES ALDH1A2, SDHA, TYR CYP1A2 39/4885ERBB2 2994/4885FYN 1924/4885
US-10995217-B2 Compounds as potential dye molecules ALDH1A2, SDHA, TYR CYP1A2 39/4885ERBB2 2994/4885FYN 1924/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.