SCHEMBL20739823

SCHEMBL20739823

CCN(CC)c1cc(OC)c(C2N(C)c3ccccc3N2C)c(OC)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.50
▸ ALDH1A1 P00352 5/20 0.41
▸ L3MBTL1 Q9Y468 1/20 0.41
▸ PDGFRB P09619 1/20 0.39
▸ MEN1 O00255 3/20 0.38
▸ KMT2A Q03164 3/20 0.38
▸ GFER P55789 2/20 0.38
▸ POLB P06746 2/20 0.38
▸ NPC1 O15118 1/20 0.38
▸ RAB9A P51151 1/20 0.38
▸ CYBB P04839 1/20 0.37
▸ NOX4 Q9NPH5 1/20 0.37
▸ NPSR1 Q6W5P4 4/20 0.36
▸ MAPT P10636 3/20 0.36
▸ MAPK1 P28482 2/20 0.36
▸ KDM4E B2RXH2 2/20 0.35
▸ BRPF1 P55201 1/20 0.35
▸ CYP1A2 P05177 1/20 0.35
▸ CYP3A4 P08684 1/20 0.35
▸ CYP2D6 P10635 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20739825 0.84 LMNA (0.54) LMNAALDH1A1L3MBTL1PDGFRBMEN1
SCHEMBL21972259 0.83 LMNA (0.58) LMNAALDH1A1L3MBTL1PDGFRBMEN1
SCHEMBL21971404 0.82 LMNA (0.58) LMNAALDH1A1PDGFRBMEN1KMT2A
SCHEMBL21972266 0.79 LMNA (0.49) LMNAALDH1A1L3MBTL1PDGFRBMEN1
SCHEMBL21970634 0.76 LMNA (0.59) LMNAALDH1A1PDGFRBMEN1KMT2A
SCHEMBL21972251 0.76 LMNA (0.49) LMNAALDH1A1PDGFRBMEN1KMT2A
SCHEMBL21972257 0.76 LMNA (0.49) LMNAALDH1A1L3MBTL1PDGFRBMEN1
SCHEMBL21972258 0.72 LMNA (0.46) LMNAPDGFRBMEN1KMT2AKDM4E
SCHEMBL20739824 0.72 LMNA (0.36) LMNAALDH1A1PDGFRBKDM4EBRPF1
SCHEMBL3423280 0.70 ALDH1A1 (0.44) LMNAALDH1A1L3MBTL1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11046655-B2 Compound and method for producing same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-06-29 — — US disclosed
EP-3416205-B1 LIGHT-EMITTING ELEMENT AND METHOD FOR MANUFACTURING SAME SUMITOMO CHEMICAL CO (JP) 2021-03-17 — — EP disclosed
US-10711091-B2 Light-emitting device and method for producing same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-07-14 — — US disclosed
US-20200140394-A1 NOVEL COMPOUND AND METHOD FOR PRODUCING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-05-07 — — US disclosed
US-20190048131-A1 LIGHT-EMITTING DEVICE AND METHOD FOR PRODUCING SAME CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2019-02-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10711091-B2 Light-emitting device and method for producing same SCO2, SUN2, SLC18A2 LMNA 919/4885ALDH1A1 327/4885L3MBTL1 1432/4885
US-20200140394-A1 NOVEL COMPOUND AND METHOD FOR PRODUCING SAME CBR3, NR2E3, NR5A2 LMNA 4733/4885ALDH1A1 1147/4885L3MBTL1 2731/4885
US-20190048131-A1 LIGHT-EMITTING DEVICE AND METHOD FOR PRODUCING SAME SCO2, SUN2, SLC18A2 LMNA 919/4885ALDH1A1 327/4885L3MBTL1 1432/4885
US-11046655-B2 Compound and method for producing same CBR3, NR5A1, NR2E3 LMNA 4570/4885ALDH1A1 1076/4885L3MBTL1 2735/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback