SCHEMBL20739824

SCHEMBL20739824

COc1cc(N(C)C)cc(OC)c1C1N(C)c2cc(N(C)C)c(N(C)C)cc2N1C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 0.36
▸ KDM4E B2RXH2 1/20 0.35
▸ ALDH1A1 P00352 1/20 0.35
▸ GLA P06280 1/20 0.35
▸ GAA P10253 1/20 0.35
▸ HPGD P15428 1/20 0.35
▸ SMN1; SMN2 Q16637 1/20 0.35
▸ HSD17B10 Q99714 1/20 0.35
▸ PDGFRB P09619 1/20 0.35
▸ NQO2 P16083 1/20 0.33
▸ SNCA P37840 1/20 0.33
▸ TUBB4A P04350 1/20 0.33
▸ TUBB P07437 1/20 0.33
▸ TUBA3C P0DPH7 1/20 0.33
▸ TUBA1B P68363 1/20 0.33
▸ TUBA4A P68366 1/20 0.33
▸ TUBB4B P68371 1/20 0.33
▸ TUBB3 Q13509 1/20 0.33
▸ TUBB2A Q13885 1/20 0.33
▸ TUBB8 Q3ZCM7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23097766 0.90 LMNA (0.33) LMNAPDGFRBNQO2
SCHEMBL20739825 0.84 LMNA (0.54) LMNAKDM4EALDH1A1GLAGAA
SCHEMBL21972266 0.82 LMNA (0.49) LMNAKDM4EALDH1A1GLAGAA
SCHEMBL20739761 0.82 CRHR1 (0.36) LMNAKDM4EALDH1A1GLAGAA
SCHEMBL23097780 0.78 PDGFRB (0.37) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL20739675 0.77 KDM4E (0.36) LMNAKDM4EALDH1A1GLAGAA
SCHEMBL21972257 0.77 LMNA (0.49) LMNAKDM4EALDH1A1GLAGAA
SCHEMBL20739683 0.75 LMNA (0.37) LMNAKDM4EALDH1A1GLAGAA
SCHEMBL21972264 0.74 LMNA (0.53) LMNAALDH1A1SMN1; SMN2PDGFRBBRD4
SCHEMBL21972251 0.74 LMNA (0.49) LMNAKDM4EALDH1A1GAAPDGFRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3416205-B1 LIGHT-EMITTING ELEMENT AND METHOD FOR MANUFACTURING SAME SUMITOMO CHEMICAL CO (JP) 2021-03-17 — — EP disclosed
US-10711091-B2 Light-emitting device and method for producing same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-07-14 — — US disclosed
US-20190048131-A1 LIGHT-EMITTING DEVICE AND METHOD FOR PRODUCING SAME CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2019-02-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10711091-B2 Light-emitting device and method for producing same SCO2, SUN2, SLC18A2 LMNA 919/4885KDM4E 3000/4885ALDH1A1 327/4885
US-20190048131-A1 LIGHT-EMITTING DEVICE AND METHOD FOR PRODUCING SAME SCO2, SUN2, SLC18A2 LMNA 919/4885KDM4E 3000/4885ALDH1A1 327/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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