Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4101948 | 0.74 | ALDH1A1 (0.31) | — | |
| SCHEMBL20503228 | 0.71 | PPARG (0.34) | — | |
| SCHEMBL1989127 | 0.69 | — | — | |
| SCHEMBL20740677 | 0.66 | DHFR (0.69) | DHFRSLC2A1 | |
| SCHEMBL20740678 | 0.65 | DHFR (0.52) | DHFRSLC2A1 | |
| SCHEMBL20740668 | 0.65 | DHFR (0.58) | DHFRSLC2A1 | |
| SCHEMBL20740674 | 0.63 | DHFR (0.56) | DHFRSLC2A1 | |
| SCHEMBL20740670 | 0.63 | DHFR (0.53) | DHFRSLC2A1 | |
| SCHEMBL20740675 | 0.63 | KMT2A (0.54) | DHFRSLC2A1 | |
| SCHEMBL8901961 | 0.62 | CYP2D6 (0.58) | DHFRSLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2194985-B1 | ANTIMALARIAL COMPOUNDS WITH FLEXIBLE SIDE-CHAINS | MEDICINES FOR MALARIA VENTURE MMV (CH) | 2019-02-20 | — | — | EP | claimed |
| EP-2194985-B1 | ANTIMALARIAL COMPOUNDS WITH FLEXIBLE SIDE-CHAINS | MEDICINES FOR MALARIA VENTURE MMV (CH) | 2019-02-20 | — | — | EP | disclosed |