Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | TSHR | P16473 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29354050 | 0.85 | TSHR (0.42) | POLBKMT2ANPSR1SMN1; SMN2TSHR | |
| SCHEMBL2507036 | 0.85 | TSHR (0.42) | POLBKMT2ANPSR1SMN1; SMN2TSHR | |
| SCHEMBL27808614 | 0.84 | TSHR (0.41) | POLBKMT2ANPSR1SMN1; SMN2TSHR | |
| Phosphine SCHEMBL28247442 | 0.84 | TSHR (0.41) | POLBKMT2ANPSR1SMN1; SMN2TSHR | |
| Hydrochloric Acid SCHEMBL30943478 | 0.84 | TSHR (0.41) | POLBKMT2ANPSR1SMN1; SMN2TSHR | |
| SCHEMBL20740857 | 0.81 | KCNMA1 (0.41) | KCNMA1POLBKMT2ANPSR1KDM4E | |
| SCHEMBL29360593 | 0.80 | TSHR (0.46) | POLBKMT2ANPSR1SMN1; SMN2TSHR | |
| Fluoride Ion SCHEMBL17601912 | 0.79 | TSHR (0.45) | POLBKMT2ANPSR1SMN1; SMN2TSHR | |
| SCHEMBL28555388 | 0.77 | TSHR (0.36) | POLBKMT2ANPSR1SMN1; SMN2TSHR | |
| SCHEMBL8623356 | 0.77 | TSHR (0.41) | POLBKMT2ANPSR1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190055223-A1 | TOXIN AND METHOD FOR PREPARING INTERMEDIATE THEREOF | SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD. (CN) | 2019-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190055223-A1 | TOXIN AND METHOD FOR PREPARING INTERMEDIATE THEREOF | VIP, HABP2, FURIN | KCNMA1 912/4885POLB 4156/4885KMT2A 4784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.