SCHEMBL20740903

SCHEMBL20740903

N#Cc1c(F)c(Br)c(Br)c(Br)c1F

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 1/20 0.33
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20596085 0.88 TRPV4 (0.33) TRPV4ATM
SCHEMBL5333617 0.88 TRPV4 (0.33) TRPV4ATM
SCHEMBL30165352 0.83 TRPV4 (0.31) TRPV4
SCHEMBL28966751 0.83 TRPV4 (0.31) TRPV4
SCHEMBL3474652 0.82 TRPV4 (0.33) TRPV4ATM
SCHEMBL8346781 0.80 TRPV4 (0.32) TRPV4ATM
SCHEMBL28966761 0.80 TRPV4 (0.32) TRPV4ATM
SCHEMBL5334905 0.78 TRPV4 (0.31) TRPV4
SCHEMBL28966745 0.78 TRPV4 (0.31) TRPV4
SCHEMBL9152960 0.78 TRPV4 (0.32) TRPV4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11069860-B2 Composition of matter for use in organic light-emitting diodes KYULUX, INC. (JP) 2021-07-20 US disclosed
US-20190058130-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES Kyulux North America, Inc. 2019-02-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11069860-B2 Composition of matter for use in organic light-emitting diodes ALDH1A2, CYBA, CRY2 TRPV4 681/4885ATM 2430/4885
US-20190058130-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES ALDH1A2, CYBA, CRY2 TRPV4 681/4885ATM 2430/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.