Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL20743442 | 0.99 | LTA4H (0.33) | LTA4HSYKKDM4EMEN1MAPT | |
| SCHEMBL24418527 | 0.99 | LTA4H (0.34) | LTA4HSYKKDM4EMEN1MAPT | |
| Hydrochloric Acid SCHEMBL20743549 | 0.97 | LTA4H (0.33) | LTA4HSYKKDM4EMEN1MAPT | |
| Hydrochloric Acid SCHEMBL20743551 | 0.97 | LTA4H (0.33) | LTA4HSYKKDM4EMEN1MAPT | |
| Trifluoroacetic Acid SCHEMBL20743545 | 0.87 | DPP4 (0.34) | LTA4H | |
| SCHEMBL20753844 | 0.84 | KIF11 (0.35) | — | |
| SCHEMBL22345226 | 0.84 | KIF11 (0.35) | — | |
| SCHEMBL22345227 | 0.84 | KIF11 (0.35) | — | |
| Trifluoroacetic Acid SCHEMBL22345229 | 0.83 | DPP4 (0.32) | LTA4H | |
| Trifluoroacetic Acid SCHEMBL20743546 | 0.83 | DPP4 (0.32) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3923727-A1 | PRE-HARVEST DESICCATION METHOD | Syngenta Crop Protection AG (CH) | 2021-12-22 | — | — | EP | disclosed |
| EP-3923723-A1 | HERBICIDAL COMPOSITIONS | Syngenta Crop Protection AG (CH) | 2021-12-22 | — | — | EP | disclosed |
| EP-3923725-A1 | HERBICIDAL COMPOSITIONS | Syngenta Crop Protection AG (CH) | 2021-12-22 | — | — | EP | disclosed |
| EP-3923722-A1 | HERBICIDAL COMPOSITIONS | Syngenta Crop Protection AG (CH) | 2021-12-22 | — | — | EP | disclosed |
| EP-3923724-A1 | HERBICIDAL COMPOSITIONS | Syngenta Crop Protection AG (CH) | 2021-12-22 | — | — | EP | disclosed |
| EP-3923726-A1 | HERBICIDAL COMPOSITIONS | Syngenta Crop Protection AG (CH) | 2021-12-22 | — | — | EP | disclosed |
| WO-2020164922-A1 | HERBICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION AG (CH) | 2020-08-20 | — | — | WO | disclosed |
| WO-2020164923-A1 | HERBICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION AG (CH) | 2020-08-20 | — | — | WO | disclosed |
| WO-2020164924-A1 | HERBICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION AG (CH) | 2020-08-20 | — | — | WO | disclosed |
| WO-2020164971-A1 | PRE-HARVEST DESICCATION METHOD | SYNGENTA CROP PROTECTION AG (CH) | 2020-08-20 | — | — | WO | disclosed |
| WO-2020164925-A1 | HERBICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION AG (CH) | 2020-08-20 | — | — | WO | disclosed |
| WO-2020164920-A1 | HERBICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION AG (CH) | 2020-08-20 | — | — | WO | disclosed |
| EP-3668855-A1 | HERBICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2020-06-24 | — | — | EP | disclosed |
| WO-2019034757-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-02-21 | — | — | WO | disclosed |