Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL20743545

COC(=O)[C@@H](N)CCC[n+]1ccc(-c2ncccn2)cn1.O=C(O)C(F)(F)F

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 6/20 0.34
DPP7 Q9UHL4 6/20 0.34
LTA4H P09960 3/20 0.32
KIF11 P52732 1/20 0.30
ANPEP P15144 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL20743546 0.96 DPP4 (0.32) DPP4DPP7LTA4H
Trifluoroacetic Acid SCHEMBL22345229 0.96 DPP4 (0.32) DPP4DPP7LTA4H
SCHEMBL24418527 0.88 LTA4H (0.34) LTA4HKIF11
Bromide SCHEMBL20743441 0.87 LTA4H (0.34) LTA4H
Bromide SCHEMBL20743442 0.86 LTA4H (0.33) LTA4H
Hydrochloric Acid SCHEMBL20743549 0.86 LTA4H (0.33) LTA4H
Hydrochloric Acid SCHEMBL20743551 0.86 LTA4H (0.33) LTA4H
Trifluoroacetic Acid SCHEMBL20743519 0.83 GRB2 (0.34) DPP4DPP7KIF11
Trifluoroacetic Acid SCHEMBL20744300 0.83 GRB2 (0.34) DPP4DPP7KIF11
SCHEMBL24001048 0.82 ARG1 (0.38) KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3923724-B1 HERBICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2023-07-26 EP disclosed
US-11618743-B2 Herbicidal compounds SYNGENTA PARTICIPATIONS AG (CH) 2023-04-04 US disclosed
US-20220192195-A1 HERBICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2022-06-23 US disclosed
US-20220159956-A1 HERBICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2022-05-26 US disclosed
US-20220142162-A1 HERBICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2022-05-12 US disclosed
US-20220125052-A1 Herbicidal Compositions SYNGENTA CROP PROTECTION AG (CH) 2022-04-28 US disclosed
US-20220125051-A1 PRE-HARVEST DESICCATION METHOD SYNGENTA CROP PROTECTION AG (CH) 2022-04-28 US disclosed
US-20220095618-A1 HERBICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2022-03-31 US disclosed
EP-3923723-A1 HERBICIDAL COMPOSITIONS Syngenta Crop Protection AG (CH) 2021-12-22 EP disclosed
EP-3923724-A1 HERBICIDAL COMPOSITIONS Syngenta Crop Protection AG (CH) 2021-12-22 EP disclosed
EP-3668855-B1 HERBICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2021-11-10 EP disclosed
US-20210009561-A1 HERBICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2021-01-14 US disclosed
WO-2020164922-A1 HERBICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2020-08-20 WO disclosed
WO-2020164920-A1 HERBICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2020-08-20 WO disclosed
WO-2020164923-A1 HERBICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2020-08-20 WO disclosed
WO-2020164924-A1 HERBICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2020-08-20 WO disclosed
WO-2020164971-A1 PRE-HARVEST DESICCATION METHOD SYNGENTA CROP PROTECTION AG (CH) 2020-08-20 WO disclosed
WO-2020164925-A1 HERBICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2020-08-20 WO disclosed
EP-3668855-A1 HERBICIDAL COMPOUNDS Syngenta Participations AG (CH) 2020-06-24 EP disclosed
WO-2019034757-A1 HERBICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2019-02-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210009561-A1 HERBICIDAL COMPOUNDS DDT, ACHE, GSTO1 DPP4 25/4885DPP7 23/4885LTA4H 1787/4885
US-20220142162-A1 HERBICIDAL COMPOSITIONS PPOX, DDT, HPD DPP4 654/4885DPP7 641/4885LTA4H 1715/4885
US-20220159956-A1 HERBICIDAL COMPOSITIONS DDT, HPD, DHFR DPP4 101/4885DPP7 91/4885LTA4H 1584/4885
US-20220095618-A1 HERBICIDAL COMPOSITIONS HPD, HACL2, AADAC DPP4 332/4885DPP7 406/4885LTA4H 88/4885
US-11618743-B2 Herbicidal compounds DDT, ACHE, GSTO1 DPP4 25/4885DPP7 23/4885LTA4H 1787/4885
US-20220125052-A1 Herbicidal Compositions DDT, HPD, DHFR DPP4 276/4885DPP7 190/4885LTA4H 2732/4885
US-20220125051-A1 PRE-HARVEST DESICCATION METHOD GMDS, TREH, DAD1 DPP4 541/4885DPP7 242/4885LTA4H 3022/4885
US-20220192195-A1 HERBICIDAL COMPOSITIONS GLO1, LCT, HACL2 DPP4 258/4885DPP7 176/4885LTA4H 456/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.