Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15515468 | 0.83 | HDAC1 (0.41) | KMT2AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL29949095 | 0.83 | HDAC1 (0.41) | KMT2AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL15505733 | 0.83 | HDAC1 (0.41) | KMT2AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL15515467 | 0.83 | HDAC1 (0.41) | KMT2AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL12488050 | 0.78 | HSD17B3 (0.35) | S1PR5 | |
| SCHEMBL12487278 | 0.76 | MAPT (0.44) | KMT2AALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL17994150 | 0.74 | AVPR1A (0.46) | — | |
| SCHEMBL12097260 | 0.69 | KMT2A (0.34) | KMT2AALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL12097264 | 0.69 | KMT2A (0.34) | KMT2AALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL15505675 | 0.69 | HDAC1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11589586-B2 | Pesticidal and parasiticidal pyrazole-isoxazoline compounds | Boehringer Ingelheim Animal Health USA Inc. (US) | 2023-02-28 | — | — | US | disclosed |
| EP-3668866-B1 | PESTICIDAL AND PARASITICIDAL PYRAZOLE-ISOXAZOLINE COMPOUNDS | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2023-01-18 | — | — | EP | disclosed |
| EP-3668866-A1 | PESTICIDAL AND PARASITICIDAL PYRAZOLE-ISOXAZOLINE COMPOUNDS | Boehringer Ingelheim Animal Health USA Inc. (US) | 2020-06-24 | — | — | EP | disclosed |
| US-20200178531-A1 | PESTICIDAL AND PARASITICIDAL PYRAZOLE-ISOXAZOLINE COMPOUNDS | Boehringer Ingelheim Animal Health USA Inc. (US) | 2020-06-11 | — | — | US | disclosed |
| WO-2019036407-A1 | PESTICIDAL AND PARASITICIDAL PYRAZOLE-ISOXAZOLINE COMPOUNDS | MERIAL, INC. (US) | 2019-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11589586-B2 | Pesticidal and parasiticidal pyrazole-isoxazoline compounds | PRDX1, PRDX5, P2RX7 | KMT2A 2293/4885ALDH1A1 1128/4885LMNA 2425/4885 |
| US-20200178531-A1 | PESTICIDAL AND PARASITICIDAL PYRAZOLE-ISOXAZOLINE COMPOUNDS | PRDX1, PRDX5, P2RX7 | KMT2A 2293/4885ALDH1A1 1128/4885LMNA 2425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.