Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | RBBP9 | O75884 | 5/20 | 0.41 |
| ▸ | PLA2G4A | P47712 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25242978 | 0.85 | ALDH1A1 (0.57) | ALDH1A1RBBP9PLA2G4ACYP1A2CYP2D6 | |
| SCHEMBL837325 | 0.83 | ALDH1A1 (0.55) | ALDH1A1RBBP9PLA2G4ACYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL14763613 | 0.81 | ALDH1A1 (0.53) | ALDH1A1RBBP9PLA2G4ACYP1A2CYP2C19 | |
| Bromide SCHEMBL29000634 | 0.81 | ALDH1A1 (0.53) | ALDH1A1RBBP9PLA2G4ACYP1A2CYP2C19 | |
| SCHEMBL18669024 | 0.81 | ALDH1A1 (0.44) | ALDH1A1RBBP9PLA2G4ACYP1A2CYP2D6 | |
| SCHEMBL27647394 | 0.78 | L3MBTL1 (0.58) | ALDH1A1PLA2G4ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL18668864 | 0.76 | PLA2G4A (0.43) | ALDH1A1RBBP9PLA2G4ACES1L3MBTL1 | |
| SCHEMBL22393879 | 0.76 | PLA2G4A (0.54) | ALDH1A1RBBP9PLA2G4ACASP3SENP8 | |
| SCHEMBL1009292 | 0.76 | — | — | |
| SCHEMBL20746452 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4204415-A1 | HETEROCYCLIC GLP-1 AGONISTS | Gasherbrum Bio, Inc. (US) | 2023-07-05 | — | — | EP | disclosed |