Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | TACR2 | P21452 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SHBG | P04278 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20746513 | 1.00 | EPHX2 (0.47) | EPHX2ALOX5PTGS1PTGS2MAPT | |
| SCHEMBL20746447 | 1.00 | EPHX2 (0.47) | EPHX2ALOX5PTGS1PTGS2MAPT | |
| SCHEMBL20746538 | 1.00 | EPHX2 (0.47) | EPHX2ALOX5PTGS1PTGS2MAPT | |
| SCHEMBL20746521 | 1.00 | EPHX2 (0.47) | EPHX2ALOX5PTGS1PTGS2MAPT | |
| SCHEMBL20746460 | 0.98 | ALOX5 (0.44) | EPHX2ALOX5PTGS1PTGS2MAPT | |
| SCHEMBL20746437 | 0.96 | ALOX5 (0.47) | EPHX2ALOX5PTGS1PTGS2MAPT | |
| SCHEMBL20746432 | 0.93 | ALOX5 (0.40) | EPHX2ALOX5PTGS1PTGS2MAPT | |
| SCHEMBL20746475 | 0.87 | CSNK1E (0.35) | EPHX2ALOX5MAPTS1PR2S1PR1 | |
| SCHEMBL20766699 | 0.84 | CYP2E1 (0.37) | EPHX2ALOX5S1PR2S1PR1HTR2A | |
| SCHEMBL20766589 | 0.84 | CYP2E1 (0.37) | EPHX2ALOX5S1PR2S1PR1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3668957-A1 | FURAN BASED COMPOSITIONS AND METHODS OF MAKING THEREOF | University of Delaware (US) | 2020-06-24 | — | — | EP | claimed |
| WO-2019036663-A1 | FURAN BASED COMPOSITIONS AND METHODS OF MAKING THEREOF | UNIVERSITY OF DELAWARE (US) | 2019-02-21 | — | — | WO | claimed |
| US-20210040055-A1 | FURAN BASED COMPOSITIONS AND METHODS OF MAKING THEREOF | UNIVERSITY OF DELAWARE (US) | 2021-02-11 | — | — | US | disclosed |
| EP-3668957-A1 | FURAN BASED COMPOSITIONS AND METHODS OF MAKING THEREOF | University of Delaware (US) | 2020-06-24 | — | — | EP | disclosed |
| WO-2019036663-A1 | FURAN BASED COMPOSITIONS AND METHODS OF MAKING THEREOF | UNIVERSITY OF DELAWARE (US) | 2019-02-21 | — | — | WO | disclosed |
| WO-2019036663-A1 | FURAN BASED COMPOSITIONS AND METHODS OF MAKING THEREOF | UNIVERSITY OF DELAWARE (US) | 2019-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210040055-A1 | FURAN BASED COMPOSITIONS AND METHODS OF MAKING THEREOF | CBR3, CBR1, FPR3 | EPHX2 841/4885ALOX5 22/4885PTGS1 1002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.