SCHEMBL20766699

SCHEMBL20766699

CCCCCCCC(c1ccc(CN)o1)c1ccc(CN)o1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2E1 P05181 2/20 0.37
CYP3A4 P08684 2/20 0.37
CYP2D6 P10635 2/20 0.37
CYP2A6 P11509 2/20 0.37
CYP2C9 P11712 2/20 0.37
CYP2B6 P20813 2/20 0.37
CYP2C19 P33261 2/20 0.37
CSNK1E P49674 1/20 0.36
ALOX5 P09917 1/20 0.36
HTR2A P28223 2/20 0.34
EPHX2 P34913 1/20 0.33
SLC2A1 P11166 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C8 P10632 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
OPRM1 P35372 1/20 0.32
S1PR2 O95136 1/20 0.32
S1PR1 P21453 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20766589 1.00 CYP2E1 (0.37) CYP2E1CYP3A4CYP2D6CYP2A6CYP2C9
SCHEMBL20783620 0.89 CYP3A4 (0.44) CYP2E1CYP3A4CYP2D6CYP2A6CYP2C9
SCHEMBL20746475 0.86 CSNK1E (0.35) CSNK1EALOX5EPHX2MEN1KMT2A
SCHEMBL20746485 0.84 EPHX2 (0.47) CYP3A4CSNK1EALOX5HTR2AEPHX2
SCHEMBL20746513 0.84 EPHX2 (0.47) CYP3A4CSNK1EALOX5HTR2AEPHX2
SCHEMBL20746432 0.84 ALOX5 (0.40) CSNK1EALOX5EPHX2MEN1KMT2A
SCHEMBL20746437 0.84 ALOX5 (0.47) CSNK1EALOX5EPHX2MEN1KMT2A
SCHEMBL20746521 0.84 EPHX2 (0.47) CYP3A4CSNK1EALOX5HTR2AEPHX2
SCHEMBL20746447 0.84 EPHX2 (0.47) CYP3A4CSNK1EALOX5HTR2AEPHX2
SCHEMBL20746538 0.84 EPHX2 (0.47) CYP3A4CSNK1EALOX5HTR2AEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11629220-B2 Renewable furan based amine curing agents for epoxy thermoset Drexel Unversity (US) 2023-04-18 US claimed
US-20200172658-A1 RENEWABLE FURAN BASED AMINE CURING AGENTS FOR EPOXY THERMOSET DREXEL UNIVERSITY (US) 2020-06-04 US claimed
US-11629220-B2 Renewable furan based amine curing agents for epoxy thermoset Drexel Unversity (US) 2023-04-18 US disclosed
EP-3672947-A1 RENEWABLE FURAN BASED AMINE CURING AGENTS FOR EPOXY THERMOSET The United States of America as represented by the Secretary of the Army (US) 2020-07-01 EP disclosed
US-20200172658-A1 RENEWABLE FURAN BASED AMINE CURING AGENTS FOR EPOXY THERMOSET DREXEL UNIVERSITY (US) 2020-06-04 US disclosed
WO-2019040389-A1 RENEWABLE FURAN BASED AMINE CURING AGENTS FOR EPOXY THERMOSET PALMESE GIUSEPPE R (US) 2019-02-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200172658-A1 RENEWABLE FURAN BASED AMINE CURING AGENTS FOR EPOXY THERMOSET EPHX2, AOC1, EPHX1 CYP2E1 432/4885CYP3A4 1895/4885CYP2D6 2493/4885
US-11629220-B2 Renewable furan based amine curing agents for epoxy thermoset EPHX2, AOC1, EPHX1 CYP2E1 432/4885CYP3A4 1895/4885CYP2D6 2493/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.