Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16351748 | 0.80 | MAPT (0.47) | ALDH1A1MAPTCYP1A2CYP2C19POLB | |
| SCHEMBL28896469 | 0.76 | ALDH1A1 (0.41) | ALDH1A1HPGDPOLBTDP1 | |
| SCHEMBL15156310 | 0.74 | KDM4E (0.36) | FDPSALDH1A1MAPTHPGDCYP1A2 | |
| SCHEMBL16351741 | 0.74 | CYP19A1 (0.51) | ALDH1A1NPSR1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL14273335 | 0.74 | FDPS (0.51) | FDPSALDH1A1NPSR1CYP2C9NPC1 | |
| SCHEMBL29607348 | 0.73 | KDM4E (0.44) | FDPSALDH1A1NPSR1CYP2C9NPC1 | |
| SCHEMBL6262371 | 0.73 | FDPS (0.51) | FDPSALDH1A1NPSR1CYP2C9SMN1; SMN2 | |
| SCHEMBL14793734 | 0.72 | THRB (0.47) | ALDH1A1THRATHRBTDP1L3MBTL1 | |
| SCHEMBL29606343 | 0.72 | PDK2 (0.46) | FDPSALDH1A1NPSR1CYP2C9NPC1 | |
| SCHEMBL29607734 | 0.72 | FDPS (0.59) | FDPSALDH1A1NPSR1CYP2C9NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2928869-B1 | 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOL DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARM SPA (IT) | 2019-02-20 | — | — | EP | disclosed |