Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | AGXT | P21549 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL434644 | 0.84 | TSHR (0.61) | TSHRIDO1AGXTTDP1L3MBTL1 | |
| SCHEMBL6832294 | 0.82 | TSHR (0.64) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL3127292 | 0.82 | TSHR (0.64) | TSHRIDO1AGXTTDP1L3MBTL1 | |
| SCHEMBL26656 | 0.81 | TSHR (0.55) | TSHRIDO1AGXTTDP1L3MBTL1 | |
| SCHEMBL223907 | 0.81 | TSHR (0.78) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL70291 | 0.79 | TSHR (0.74) | TSHRIDO1AGXTTDP1L3MBTL1 | |
| SCHEMBL53267 | 0.79 | TSHR (0.74) | TSHRIDO1AGXTTDP1L3MBTL1 | |
| SCHEMBL434643 | 0.78 | TSHR (0.58) | TSHRIDO1AGXTTDP1L3MBTL1 | |
| SCHEMBL5353833 | 0.76 | TSHR (0.61) | TSHRIDO1AGXTTDP1L3MBTL1 | |
| SCHEMBL5311581 | 0.75 | TSHR (1.00) | TSHRIDO1AGXTALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2928869-B1 | 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOL DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARM SPA (IT) | 2019-02-20 | — | — | EP | disclosed |