Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.74 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | AGXT | P21549 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 5/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL70291 | 1.00 | TSHR (0.74) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL223907 | 0.97 | TSHR (0.78) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL434644 | 0.91 | TSHR (0.61) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL434643 | 0.89 | TSHR (0.58) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL5353833 | 0.85 | TSHR (0.61) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL4675777 | 0.85 | TSHR (0.61) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL71046 | 0.85 | TSHR (0.61) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL987625 | 0.85 | TSHR (0.61) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL5311581 | 0.85 | TSHR (1.00) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL27380 | 0.85 | TSHR (1.00) | TSHRIDO1AGXTALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2544 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119899238-A | Condensed-cyclic compound, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2025-04-29 | — | — | CN | claimed |
| WO-2025053792-A1 | COLLECTIVE SYNTHESIS OF PHANTOMOLIN FAMILY THROUGH TOTAL SYNTHESIS OF THE SESQUITERPENE LACTONE MOLEPHANTIN | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2025-03-13 | — | — | WO | claimed |
| EP-3180371-B1 | ZIEGLER-NATTA CATALYST FOR HIGH TEMPERATURE POLYMERIZATION | NOVA CHEM INT SA (CH) | 2024-10-30 | — | — | EP | claimed |
| CN-118239918-A | Preparation method of iridoid compound | 山东新时代药业有限公司 | 2024-06-25 | — | — | CN | claimed |
| CN-118221628-A | Preparation method of iridoid derivative | 山东新时代药业有限公司 | 2024-06-21 | — | — | CN | claimed |
| EP-3386920-B1 | SYNTHESIS OF MAGNESIUM DICHLORIDE SUPPORT FOR THE AST OFF-LINE ZN CATALYST WITH A PLUG FLOW REACTOR (PFR) | NOVA CHEM INT SA (CH) | 2023-08-09 | — | — | EP | claimed |
| US-10981939-B2 | Process for the preparation of 4-[(1-hydroxy-1,3-dihydro-2,1-benzoxaborol-5-yl) oxy] benzonitrile (Crisaborole) | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) | 2021-04-20 | — | — | US | claimed |
| WO-2020119205-A1 | RADIOACTIVE FLUORINE-LABELED LAROTRECTINIB COMPOUND AND PREPARATION METHOD THEREFOR | 上海健康医学院 | 2020-06-18 | — | — | WO | claimed |
| US-10662202-B2 | Synthesis of cephalosporin compounds | MERCK SHARP & DOHM CORP. (US) | 2020-05-26 | — | — | US | claimed |
| US-10632099-B2 | Non-aromatic difluoro analogues of resorcylic acid lactones | UNIVERSITY OF NORTH CAROLINA AT GREENSBORO (US) | 2020-04-28 | — | — | US | claimed |
| CN-103189341-A | Chiral intermediates useful for the preparation of hydroxyphosphine ligands | UNITED PHOSPHORUS LTD | 2013-07-03 | — | — | CN | claimed |
| WO-2012083261-A1 | BLOOD BRAIN BARRIER-PENETRATING OXIMES FOR CHOLISTENERASES REACTIVATION | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2012-06-21 | — | — | WO | claimed |
| US-8193270-B2 | Method of making composites and nanocomposites | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-06-05 | — | — | US | claimed |
| WO-2012059807-A1 | CHIRAL INTERMEDIATES USEFUL FOR THE PREPARATION OF HYDROXYPHOSPHINE LIGANDS | UNITED PHOSPHORUS LIMITED (IN) | 2012-05-10 | — | — | WO | claimed |
| CN-101812060-B | Simple novel method for preparing high-purity Sprycel, and intermediate compound | NANJING CAVENDISH BIOENGINEERING TECHNOLOGY CO LTD | 2011-08-17 | — | — | CN | claimed |
| US-7915306-B2 | For therapy of inflammatory or autoimmune disorders | EISAI CO., LTD. (JP) | 2011-03-29 | — | — | US | claimed |
| CN-100503608-C | Deazapurines and their use | EISAI CO LTD (JP) | 2009-06-24 | — | — | CN | claimed |
| US-7449586-B2 | Processes for the preparation of CGRP-receptor antagonists and intermediates thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-11-11 | — | — | US | claimed |
| WO-2006060678-A2 | NOVEL PROCESSES FOR THE PREPARATION OF CGRP-RECEPTOR ANTAGONISTS AND INTERMEDIATES THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-06-08 | — | — | WO | claimed |
| US-20060122250-A1 | Novel processes for the preparation of CGRP-receptor antagonists and intermediates thereof | BRISTOL-MYERS SQUIBB COMPANY | 2006-06-08 | — | — | US | claimed |