Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 8/20 | 0.48 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 2/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | PAK4 | O96013 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15576185 | 0.92 | CA2 (0.44) | ADKDOT1LCA2RETDAPK3 | |
| SCHEMBL2611617 | 0.90 | CA2 (0.52) | ADKDOT1LCA2HTTHIF1A | |
| SCHEMBL2611652 | 0.84 | ADK (0.42) | ADKDOT1LCA2NPC1GALR3 | |
| SCHEMBL17131308 | 0.82 | ADK (0.54) | ADKDOT1LCA2NPC1GALR3 | |
| SCHEMBL20643708 | 0.82 | CA2 (0.52) | ADKCA2PRMT5METTL3 | |
| SCHEMBL19625183 | 0.82 | CA2 (0.52) | ADKCA2PRMT5METTL3 | |
| SCHEMBL22386563 | 0.82 | CA2 (0.44) | ADKDOT1LCA2RETDAPK3 | |
| SCHEMBL17131312 | 0.81 | ADK (0.55) | ADKDOT1LNPC1GALR3S1PR4 | |
| SCHEMBL17131326 | 0.81 | ADK (0.55) | ADKDOT1LNPC1GALR3S1PR4 | |
| SCHEMBL17131291 | 0.81 | ADK (0.43) | ADKDOT1LCA2NPC1GALR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3091026-B1 | DISULFIDE-LINKED REVERSIBLE TERMINATORS | CENTRILLION TECH HOLDINGS CORP (KY) | 2019-02-20 | — | — | EP | disclosed |