Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 3/20 | 0.42 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | FGFR2 | P21802 | 8/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.35 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GALR3 | O60755 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | UBA1 | P22314 | 1/20 | 0.34 |
| ▸ | NAE1 | Q13564 | 1/20 | 0.34 |
| ▸ | UBA3 | Q8TBC4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18307354 | 0.91 | ADK (0.44) | ADKDOT1LCA2FGFR2PRMT5 | |
| SCHEMBL2611654 | 0.87 | CA2 (0.41) | ADKDOT1LCA2FGFR2PRMT5 | |
| SCHEMBL10022897 | 0.86 | CA2 (0.41) | ADKDOT1LCA2FGFR2PRMT5 | |
| SCHEMBL887484 | 0.86 | CA2 (0.41) | ADKDOT1LCA2FGFR2PRMT5 | |
| SCHEMBL12047379 | 0.86 | CA2 (0.41) | ADKDOT1LCA2FGFR2PRMT5 | |
| SCHEMBL2611653 | 0.85 | CA2 (0.31) | ADKCA2 | |
| SCHEMBL2611617 | 0.84 | CA2 (0.52) | ADKDOT1LCA2PRMT5METTL3 | |
| SCHEMBL20748424 | 0.84 | ADK (0.48) | ADKDOT1LCA2PRMT5METTL3 | |
| SCHEMBL2611651 | 0.83 | ADK (0.52) | ADKDOT1LRAB9A | |
| SCHEMBL10022898 | 0.83 | ADK (0.52) | ADKDOT1LRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9388464-B2 | Modified nucleotides | ILLUMINA CAMBRIDGE LIMITED (GB) | 2016-07-12 | — | — | US | disclosed |
| US-20160032378-A1 | MODIFIED NUCLEOTIDES | SOLEXA LIMITED (GB) | 2016-02-04 | — | — | US | disclosed |
| US-9121060-B2 | Modified nucleotides | ILLUMINA CAMBRIDGE LIMITED (GB) | 2015-09-01 | — | — | US | disclosed |
| US-20130197209-A1 | MODIFIED NUCLEOTIDES | ILLUMINA CAMBRIDGE LIMITED (GB) | 2013-08-01 | — | — | US | disclosed |
| US-20120095201-A1 | MODIFIED NUCLEOTIDES | ILLUMINA CAMBRIDGE LIMITED (GB) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130197209-A1 | MODIFIED NUCLEOTIDES | ADAR, NT5C2, NSUN2 | ADK 167/4885DOT1L 561/4885CA2 1770/4885 |
| US-20120095201-A1 | MODIFIED NUCLEOTIDES | RNMT, NSUN2, NSUN3 | ADK 123/4885DOT1L 1647/4885CA2 3829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.