Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CCL2 | P13500 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21779763 | 1.00 | HTR2A (0.41) | HTR2AHTR6BRD4CCL2SIGMAR1 | |
| SCHEMBL4369384 | 0.78 | SIGMAR1 (0.45) | HTR2AHTR6BRD4CCL2SIGMAR1 | |
| SCHEMBL28506975 | 0.78 | HTR2A (0.43) | HTR2AHTR6BRD4CCL2SIGMAR1 | |
| SCHEMBL28520674 | 0.78 | HTR2A (0.43) | HTR2AHTR6BRD4CCL2SIGMAR1 | |
| SCHEMBL28516494 | 0.78 | HTR2A (0.43) | HTR2AHTR6BRD4CCL2SIGMAR1 | |
| SCHEMBL13176529 | 0.77 | HTR6 (0.41) | HTR2AHTR6BRD4CCL2SIGMAR1 | |
| SCHEMBL13024685 | 0.77 | HTR6 (0.41) | HTR2AHTR6BRD4CCL2SIGMAR1 | |
| SCHEMBL13177005 | 0.77 | HTR6 (0.41) | HTR2AHTR6BRD4CCL2SIGMAR1 | |
| SCHEMBL12715242 | 0.77 | BRD4 (0.38) | HTR2AHTR6BRD4CCL2SIGMAR1 | |
| SCHEMBL19074698 | 0.75 | AOC1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3444860-A1 | ORGANIC LIGHT-EMITTING DEVICE AND APPARATUS INCLUDING THE SAME | Samsung Display Co., Ltd. (KR) | 2019-02-20 | — | — | EP | disclosed |