SCHEMBL20749070

SCHEMBL20749070

COC(=O)CCC1=C(Cl)C=CCC=C1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.40
TSHR P16473 2/20 0.38
KDM4E B2RXH2 2/20 0.36
KMT2A Q03164 2/20 0.36
ALDH1A1 P00352 2/20 0.36
MAPT P10636 2/20 0.36
HSD17B10 Q99714 2/20 0.36
LMNA P02545 1/20 0.36
HTT P42858 1/20 0.36
KAT2B Q92831 3/20 0.35
CYP11B1 P15538 1/20 0.35
CYP11B2 P19099 1/20 0.35
MEN1 O00255 1/20 0.34
EGFR P00533 1/20 0.33
HPGD P15428 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1055501 0.71 TSHR (0.41) L3MBTL1TSHRKDM4EKMT2AALDH1A1
SCHEMBL9755827 0.65 TSHR (0.59) L3MBTL1TSHRKDM4EKMT2AALDH1A1
SCHEMBL197699 0.63 CYP11B1 (0.58) L3MBTL1KDM4EKMT2AALDH1A1HTT
SCHEMBL22922181 0.63 CYP4F2 (0.59) TSHRKMT2AALDH1A1MAPTHSD17B10
SCHEMBL1057171 0.62 TSHR (0.43) L3MBTL1TSHRKDM4EKMT2AALDH1A1
SCHEMBL24132583 0.61 L3MBTL1 (0.42) L3MBTL1TSHRKMT2AALDH1A1MAPT
SCHEMBL21679094 0.61 CYP11B1 (0.46) L3MBTL1TSHRKDM4EKMT2AALDH1A1
SCHEMBL22307574 0.61 TSHR (0.41) L3MBTL1TSHRKDM4EKMT2AALDH1A1
SCHEMBL5348780 0.61 TAAR1 (0.50) TSHRKDM4EKMT2AALDH1A1LMNA
SCHEMBL20730062 0.60 TSHR (0.38) TSHRKDM4EKMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3443959-A1 SULFAMATE DERIVATIVE COMPOUNDS FOR USE IN TREATING OR ALLEVIATING PAIN Bio-Pharm Solutions Co., Ltd. (KR) 2019-02-20 EP disclosed