Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL968532 | 0.81 | HSP90AB1 (0.40) | TSHRKMT2AALDH1A1HSD17B10LMNA | |
| SCHEMBL20730062 | 0.80 | TSHR (0.38) | TSHRKMT2AALDH1A1HSD17B10LMNA | |
| SCHEMBL20570288 | 0.77 | KEAP1 (0.39) | ALDH1A1HSD17B10LMNAMAPTHTT | |
| SCHEMBL23470149 | 0.75 | MYC (0.32) | ALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL13084165 | 0.73 | TSHR (0.36) | TSHRKMT2AALDH1A1HSD17B10LMNA | |
| SCHEMBL28656723 | 0.72 | TSHR (0.35) | TSHRKMT2AALDH1A1HSD17B10LMNA | |
| SCHEMBL20392315 | 0.72 | HSP90AB1 (0.33) | KMT2AALDH1A1HSD17B10LMNAMAPT | |
| SCHEMBL20749070 | 0.71 | L3MBTL1 (0.40) | TSHRKMT2AALDH1A1HSD17B10LMNA | |
| SCHEMBL24454861 | 0.68 | DAO (0.33) | — | |
| SCHEMBL14725572 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389572-B2 | Therapeutic delivery of carbon monoxide | HEMOCORM LIMITED (GB) | 2013-03-05 | — | — | US | disclosed |
| US-8389572-B2 | Therapeutic delivery of carbon monoxide | HEMOCORM LIMITED (GB) | 2013-03-05 | — | — | US | disclosed |
| US-8389572-B2 | Therapeutic delivery of carbon monoxide | HEMOCORM LIMITED (GB) | 2013-03-05 | — | — | US | disclosed |
| US-20110015263-A1 | THERAPEUTIC DELIVERY OF CARBON MONOXIDE | HEMOCORM LIMITED | 2011-01-20 | — | — | US | disclosed |
| US-20110015263-A1 | THERAPEUTIC DELIVERY OF CARBON MONOXIDE | HEMOCORM LIMITED | 2011-01-20 | — | — | US | disclosed |
| US-20110015263-A1 | THERAPEUTIC DELIVERY OF CARBON MONOXIDE | HEMOCORM LIMITED | 2011-01-20 | — | — | US | disclosed |
| WO-2007085806-A2 | THERAPEUTIC DELIVERY OF CARBON MONOXIDE | HEMOCORM LIMITED (GB) | 2007-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110015263-A1 | THERAPEUTIC DELIVERY OF CARBON MONOXIDE | MB, TFRC, CYC1 | TSHR 1712/4885KMT2A 3895/4885ALDH1A1 870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.