Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23734289 | 0.85 | TRPA1 (0.44) | TRPA1FDPSGABRA1GABRB2CYP3A4 | |
| SCHEMBL14895419 | 0.83 | GABRA1 (0.50) | TRPA1GABRA1GABRB2ESR1KCNH2 | |
| SCHEMBL3803877 | 0.82 | TLR8 (0.37) | TRPA1FDPSGABRA1GABRB2CYP3A4 | |
| SCHEMBL10693501 | 0.82 | FDPS (0.38) | FDPSCYP3A4ALOX15CASP1CASP7 | |
| SCHEMBL16197829 | 0.79 | FDPS (0.39) | FDPSGABRA1GABRB2ESR1KCNH2 | |
| SCHEMBL4931748 | 0.79 | FDPS (0.39) | FDPSGABRA1GABRB2ESR1KCNH2 | |
| SCHEMBL3391358 | 0.79 | FDPS (0.39) | TRPA1FDPSCYP3A4ALOX15CASP1 | |
| SCHEMBL270111 | 0.79 | GABRA1 (0.52) | FDPSGABRA1GABRB2CYP3A4ALOX15 | |
| SCHEMBL3068875 | 0.79 | FDPS (0.41) | FDPSCYP3A4ALOX15CASP1CASP7 | |
| SCHEMBL765679 | 0.78 | HSPA5 (0.48) | TRPA1GABRA1GABRB2KCNH2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3443959-A1 | SULFAMATE DERIVATIVE COMPOUNDS FOR USE IN TREATING OR ALLEVIATING PAIN | Bio-Pharm Solutions Co., Ltd. (KR) | 2019-02-20 | — | — | EP | disclosed |