SCHEMBL20749339

SCHEMBL20749339

Cc1ccc(-c2ccc(SC#N)cc2)nn1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.42
ALDH1A1 P00352 4/20 0.42
CA2 P00918 1/20 0.36
CA5A P35218 1/20 0.36
NPC1 O15118 3/20 0.36
RAB9A P51151 3/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
LMNA P02545 1/20 0.36
NFKB1 P19838 1/20 0.36
NFKB2 Q00653 1/20 0.36
RELA Q04206 1/20 0.36
KDM4E B2RXH2 2/20 0.33
CYP1A2 P05177 2/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
PKM P14618 2/20 0.33
POLB P06746 1/20 0.33
MYC P01106 1/20 0.32
WDR5 P61964 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17051575 0.79 NPC1 (0.44) MAPTALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL2615847 0.78 NPC1 (0.43) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL6676853 0.77 GAA (0.50) ALDH1A1KDM4EL3MBTL1
SCHEMBL10000239 0.73 NPC1 (0.53) MAPTALDH1A1NPC1RAB9ASMN1; SMN2
Ammonia Solution, Strong SCHEMBL28862433 0.71 NPC1 (0.52) MAPTALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL10000247 0.71 NPC1 (0.52) MAPTALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL17051572 0.71 NPC1 (0.52) MAPTALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL1521691 0.71 NPC1 (0.35) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL23084949 0.70 MAPT (0.45) MAPTALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL10165319 0.70 RAB9A (0.52) MAPTALDH1A1NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2799516-B1 LIQUID CRYSTAL MATERIAL OF SMECTIC PHASE IN HIGH SCATTERING STATE AND DISPLAY DEVICE THEREOF HALATION PHOTONICS CORP (CN) 2019-02-20 EP disclosed