SCHEMBL10165319

SCHEMBL10165319

Cc1ccc(-c2ccc(F)cc2)nn1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 9/20 0.52
NPC1 O15118 9/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
ALDH1A1 P00352 5/20 0.44
L3MBTL1 Q9Y468 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.40
MAPT P10636 2/20 0.40
CASP3 P42574 2/20 0.40
SENP8 Q96LD8 2/20 0.40
SENP7 Q9BQF6 2/20 0.40
SENP6 Q9GZR1 2/20 0.40
LMNA P02545 2/20 0.40
POLB P06746 1/20 0.40
MAOB P27338 1/20 0.39
ALDH1A3 P47895 1/20 0.39
ACHE P22303 1/20 0.39
ALOX5 P09917 1/20 0.38
MET P08581 1/20 0.38
NFKB1 P19838 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17051575 0.89 NPC1 (0.44) RAB9ANPC1MEN1KMT2AALDH1A1
SCHEMBL10000239 0.82 NPC1 (0.53) RAB9ANPC1MEN1KMT2AALDH1A1
SCHEMBL13745274 0.81 MET (0.52) RAB9ANPC1MEN1KMT2AALDH1A1
SCHEMBL10000247 0.80 NPC1 (0.52) RAB9ANPC1MEN1KMT2AALDH1A1
SCHEMBL17051572 0.80 NPC1 (0.52) RAB9ANPC1MEN1KMT2AALDH1A1
SCHEMBL23084949 0.78 MAPT (0.45) RAB9ANPC1MEN1KMT2AALDH1A1
SCHEMBL15888366 0.78 SLC6A2 (0.47) RAB9ANPC1ALDH1A1L3MBTL1SMN1; SMN2
SCHEMBL17185269 0.78 METAP2 (0.39) RAB9ANPC1MEN1KMT2AL3MBTL1
SCHEMBL21550488 0.78 NPC1 (0.46) RAB9ANPC1MEN1KMT2AALDH1A1
SCHEMBL2615845 0.78 KIF11 (0.45) ALDH1A1LMNAMAOBNFKB1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025085347-A1 IL4I1 INHIBITORS AND USES THEREOF MERCK SHARP & DOHME LLC (US) 2025-04-24 WO disclosed
US-20230183279-A1 ORGANOMETALLIC COMPLEX, LIGHT EMITTING DIODE, AND ELECTRONIC DEVICE KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2023-06-15 US disclosed
US-8785445-B2 7-phenoxychroman carboxylic acid derivatives ARRAY BIOPHARMA INC. (US) 2014-07-22 US disclosed
US-8716289-B2 Carbamate derivatives of alkyl-heterocycles, preparation thereof and therapeutic use thereof SANOFI (FR) 2014-05-06 US disclosed
US-8716289-B2 Carbamate derivatives of alkyl-heterocycles, preparation thereof and therapeutic use thereof SANOFI (FR) 2014-05-06 US disclosed
US-20120015950-A1 CARBAMATE DERIVATIVES OF ALKYL-HETEROCYCLES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF SANOFI-AVENTIS (FR) 2012-01-19 US disclosed
US-20120015950-A1 CARBAMATE DERIVATIVES OF ALKYL-HETEROCYCLES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF SANOFI-AVENTIS (FR) 2012-01-19 US disclosed
WO-2010075200-A1 7-PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES ARRAY BIOPHARMA INC. (US) 2010-07-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120015950-A1 CARBAMATE DERIVATIVES OF ALKYL-HETEROCYCLES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF INTS9, CDK8, SCN8A RAB9A 331/4885NPC1 1821/4885MEN1 812/4885
US-20230183279-A1 ORGANOMETALLIC COMPLEX, LIGHT EMITTING DIODE, AND ELECTRONIC DEVICE NR2E3, CRY1, GRK1 RAB9A 2685/4885NPC1 4328/4885MEN1 249/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.