Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 7/20 | 0.42 |
| ▸ | CDK8 | P49336 | 7/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | CDK19 | Q9BWU1 | 2/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | HAVCR2 | Q8TDQ0 | 3/20 | 0.37 |
| ▸ | BRAF | P15056 | 2/20 | 0.35 |
| ▸ | LATS1 | O95835 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CMA1 | P23946 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8526792 | 0.75 | CSNK2A1 (0.55) | CSNK2A1MAPTCMA1AHR | |
| SCHEMBL9001704 | 0.72 | CYP11B1 (0.47) | CCNCCDK8CDK19CYP11B1CYP11B2 | |
| SCHEMBL9004441 | 0.72 | CSNK2A1 (0.50) | CSNK2A1CMA1AHR | |
| SCHEMBL10289632 | 0.68 | GPR84 (0.48) | CSNK2A1MAPTCMA1AHR | |
| SCHEMBL11448149 | 0.68 | CCNC (0.60) | CCNCCDK8LATS1MAPT | |
| SCHEMBL17785829 | 0.67 | CSNK2A1 (0.45) | CSNK2A1TLR8TLR7HAVCR2CMA1 | |
| SCHEMBL8527561 | 0.66 | CSNK2A1 (0.51) | CSNK2A1CMA1AHR | |
| SCHEMBL19441232 | 0.66 | CYP2C19 (0.49) | CCNCCDK8MAPT | |
| SCHEMBL10268296 | 0.66 | — | — | |
| SCHEMBL31651986 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3157912-B1 | PARASITICIDAL COMPOSITIONS COMPRISING INDOLE DERIVATIVES, METHODS AND USES THEREOF | MERIAL INC (US) | 2019-02-20 | — | — | EP | disclosed |