SCHEMBL20751817

SCHEMBL20751817

CC1(N)C(c2ccccc2)=CC=C[C@H]1c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 16/20 0.39
MAOB P27338 15/20 0.39
MAOA P21397 14/20 0.39
MEN1 O00255 1/20 0.34
GAA P10253 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21539400 0.77 KDM1A (0.37) KDM1AMAOBMAOA
SCHEMBL23096888 0.74
SCHEMBL21765387 0.72 KDM1A (0.39) KDM1AMAOBMAOAMEN1GAA
SCHEMBL1153469 0.71 KDM1A (0.44) KDM1AMAOBMAOA
SCHEMBL28693074 0.69 KDM1A (0.35) KDM1AMAOBMAOAMEN1GAA
SCHEMBL28803293 0.69 MAOB (0.32) MAOBMAOA
SCHEMBL2839391 0.67
SCHEMBL2839389 0.67 KDM1A (0.33) KDM1AMAOBMAOA
SCHEMBL734440 0.66 KDM1A (0.38) KDM1AMAOBMAOA
SCHEMBL529869 0.66 LMNA (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3444259-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME Samsung Electronics Co., Ltd. (KR) 2019-02-20 EP disclosed