SCHEMBL28803293

SCHEMBL28803293

CC1(F)C(c2ccccc2)=CC=CC1N

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAOB P27338 6/20 0.32
MAOA P21397 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28895891 0.79 KDM1A (0.43) MAOB
SCHEMBL28129607 0.79 MAOB (0.32) MAOBMAOA
Hydrochloric Acid SCHEMBL28474112 0.78 MAOB (0.34) MAOBMAOA
SCHEMBL4758887 0.76 CA12 (0.35)
SCHEMBL20751817 0.69 KDM1A (0.39) MAOBMAOA
SCHEMBL28496560 0.68
SCHEMBL27852264 0.67
SCHEMBL529869 0.66 LMNA (0.40)
SCHEMBL30613551 0.66
SCHEMBL27511534 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115490751-A Factor D inhibitors 拜奥克里斯特制药公司 2022-12-20 CN disclosed
CN-109121414-B Benzopyrazole compounds and analogs thereof 拜奥克里斯特制药公司 2022-07-05 CN disclosed