Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2075197 | 0.86 | CYP3A4 (0.40) | CYP3A4ALOX15LMNAPTPN1STAT3 | |
| SCHEMBL63131 | 0.78 | CYP3A4 (0.67) | CYP3A4ALOX15LMNAPTPN1STAT3 | |
| SCHEMBL62190 | 0.77 | ALDH1A1 (0.40) | CYP3A4LMNAMEN1KMT2A | |
| Bisabolol Acetate SCHEMBL4279285 | 0.63 | LMNA (1.00) | CYP3A4ALOX15LMNAPTPN1STAT3 | |
| SCHEMBL62675 | 0.61 | TSHR (0.36) | CYP3A4LMNAMEN1MAPK1KMT2A | |
| Dimethylamine SCHEMBL4978247 | 0.59 | CYP3A4 (0.73) | CYP3A4ALOX15LMNAPTPN1STAT3 | |
| SCHEMBL3053446 | 0.58 | ALOX15 (0.74) | CYP3A4ALOX15LMNAPTPN1STAT3 | |
| SCHEMBL15950879 | 0.58 | MAPT (0.51) | CYP3A4ALOX15LMNAMEN1MAPK1 | |
| Levomenol SCHEMBL28249420 | 0.57 | CYP3A4 (0.64) | CYP3A4ALOX15LMNAPTPN1STAT3 | |
| SCHEMBL13177710 | 0.57 | ALOX15 (0.72) | CYP3A4ALOX15LMNAPTPN1STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7906496-B2 | Carboxylic acid derivatives | DSM IP ASSETS B.V. (NL) | 2011-03-15 | — | — | US | disclosed |