Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 3/20 | 0.50 |
| ▸ | FEN1 | P39748 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PER2 | O15055 | 1/20 | 0.38 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.38 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15915546 | 0.79 | ALOX5AP (0.41) | ALOX5APFEN1TP53MGLLPOLB | |
| SCHEMBL29190662 | 0.79 | ALOX5AP (0.47) | ALOX5APFEN1MEN1KMT2ATP53 | |
| SCHEMBL15786413 | 0.77 | PARP1 (0.47) | ALOX5APFEN1PARP1TP53 | |
| SCHEMBL3987697 | 0.77 | ALOX5AP (0.41) | ALOX5APFEN1PARP1TP53ALDH1A1 | |
| SCHEMBL12163537 | 0.75 | ALOX5AP (0.43) | ALOX5APFEN1MEN1KMT2APARP1 | |
| SCHEMBL22041218 | 0.75 | FAAH (0.44) | ALOX5APFEN1TP53ALDH1A1MGLL | |
| SCHEMBL15419716 | 0.75 | MEN1 (0.40) | MEN1KMT2ASMN1; SMN2ALDH1A1MGLL | |
| SCHEMBL14355849 | 0.75 | ADRA2C (0.49) | ALOX5APFEN1KMT2APOLB | |
| SCHEMBL15916682 | 0.74 | CA1 (0.46) | ALOX5APFEN1TP53MGLLPOLB | |
| SCHEMBL14356048 | 0.73 | ADRB1 (0.49) | ALDH1A1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2928891-B1 | PROTEIN KINASE C INHIBITORS AND USES THEREOF | RIGEL PHARMACEUTICALS INC (US) | 2019-02-20 | — | — | EP | disclosed |