SCHEMBL20754121

SCHEMBL20754121

c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc4c3oc3cc(-c5ccc6c7ccccc7n(-c7ccccc7)c6c5)ccc34)n2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.38
ATM Q13315 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
PRKDC P78527 4/20 0.36
ALOX5 P09917 2/20 0.36
MAPT P10636 4/20 0.32
PIK3CD O00329 2/20 0.32
PIK3CB P42338 2/20 0.32
PIK3CA P42336 1/20 0.32
PIK3CG P48736 1/20 0.32
TSHR P16473 5/20 0.31
HSD17B10 Q99714 3/20 0.31
MAPK1 P28482 2/20 0.31
LMNA P02545 1/20 0.31
ALDH1A1 P00352 4/20 0.31
POLB P06746 2/20 0.31
MEN1 O00255 1/20 0.31
BRCA1 P38398 1/20 0.31
KMT2A Q03164 1/20 0.31
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22329804 0.98 KDM4E (0.38) KDM4EATML3MBTL1PRKDCALOX5
SCHEMBL21573689 0.97 KDM4E (0.36) KDM4EATML3MBTL1PRKDCALOX5
SCHEMBL23948002 0.97 ALOX5 (0.39) KDM4EATML3MBTL1PRKDCALOX5
SCHEMBL22257961 0.97 PRKDC (0.36) KDM4EATML3MBTL1PRKDCALOX5
SCHEMBL23947568 0.96 ALOX5 (0.38) KDM4EATML3MBTL1PRKDCALOX5
SCHEMBL22330237 0.96 KDM4E (0.37) KDM4EATML3MBTL1PRKDCALOX5
SCHEMBL20754155 0.95 KDM4E (0.38) KDM4EATML3MBTL1PRKDCALOX5
SCHEMBL23947998 0.94 ALOX5 (0.37) KDM4EATML3MBTL1PRKDCALOX5
SCHEMBL23947794 0.94 ALOX5 (0.37) KDM4EATML3MBTL1PRKDCALOX5
SCHEMBL23947489 0.94 ALOX5 (0.42) KDM4EATML3MBTL1PRKDCALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230301183-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-09-21 US disclosed
US-20230301183-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-09-21 US disclosed
US-20230263054-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-08-17 US disclosed
US-20230263054-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-08-17 US disclosed
US-20230172065-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-06-01 US disclosed
US-20230172065-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-06-01 US disclosed
US-20230150987-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-05-18 US disclosed
US-20230150987-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-05-18 US disclosed
WO-2022025714-A1 ORGANIC LIGHT EMITTING DEVICE 주식회사 엘지화학 2022-02-03 WO disclosed
WO-2022015084-A1 ORGANIC LIGHT-EMITTING ELEMENT 주식회사 엘지화학 2022-01-20 WO disclosed
US-20200231578-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2020-07-23 US disclosed
US-20190058131-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2019-02-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150987-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES SLCO2B1, SLCO2A1, SLCO1B3 KDM4E 3745/4885ATM 4632/4885L3MBTL1 3258/4885
US-20230172065-A1 ORGANIC LIGHT EMITTING DEVICE CRY1, CYP1A2, CYP1A1 KDM4E 2372/4885ATM 2759/4885L3MBTL1 1309/4885
US-20230301183-A1 ORGANIC LIGHT EMITTING DEVICE CRY1, CRY2, CYP1A1 KDM4E 3655/4885ATM 2369/4885L3MBTL1 1106/4885
US-20200231578-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES SLCO2B1, SLCO2A1, SLCO1B3 KDM4E 3745/4885ATM 4632/4885L3MBTL1 3258/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.