Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.42 |
| ▸ | MAOA | P21397 | 3/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 6/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.40 |
| ▸ | P4HB | P07237 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GPR183 | P32249 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22733788 | 0.84 | HDAC3 (0.45) | KDM4EPOLB | |
| SCHEMBL22733789 | 0.84 | HDAC3 (0.45) | KDM4EPOLB | |
| SCHEMBL20754750 | 0.79 | TBXAS1 (0.38) | MAOBCYP1A2NPC1RAB9AKDM4E | |
| SCHEMBL20754505 | 0.79 | LDHA (0.51) | MAOBMAOACYP1A1CYP1B1 | |
| SCHEMBL22733793 | 0.79 | LDHA (0.51) | MAOBMAOACYP1A1CYP1B1 | |
| SCHEMBL20746319 | 0.77 | TBXAS1 (0.40) | MAOBCYP1A2NPC1RAB9AKDM4E | |
| SCHEMBL20746318 | 0.77 | TBXAS1 (0.40) | MAOBCYP1A2NPC1RAB9AKDM4E | |
| SCHEMBL28404528 | 0.76 | TNFRSF1A (0.53) | MAOBMAOACYP1A1CYP1B1NPC1 | |
| SCHEMBL20754708 | 0.74 | MAOB (0.38) | MAOBMAOACYP1A2NPC1RAB9A | |
| SCHEMBL28413016 | 0.73 | MAOB (0.49) | MAOBMAOACYP1B1P4HBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019036607-A1 | IMIDAZOLE-BASED ANTICANCER AGENTS AND DERIVATIVES THEREOF, AND METHODS OF MAKING AND USING SAME | THE UNIVERSITY OF TOLEDO (US) | 2019-02-21 | — | — | WO | disclosed |