Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 6/20 | 0.38 |
| ▸ | MAOB | P27338 | 4/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20746472 | 0.85 | KMT2A (0.44) | HDAC8KMT2AMEN1LMNAMAPT | |
| SCHEMBL20746471 | 0.85 | KMT2A (0.44) | HDAC8KMT2AMEN1LMNAMAPT | |
| SCHEMBL28404803 | 0.80 | MAPT (0.52) | MAOBLMNAMAPTALDH1A1HDAC2 | |
| SCHEMBL20746318 | 0.79 | TBXAS1 (0.40) | TBXAS1MAOBKMT2AMEN1CYP1A2 | |
| SCHEMBL20746319 | 0.79 | TBXAS1 (0.40) | TBXAS1MAOBKMT2AMEN1CYP1A2 | |
| SCHEMBL20754524 | 0.79 | MAOB (0.42) | MAOBCYP1A2KDM4ENPC1RAB9A | |
| SCHEMBL20754708 | 0.76 | MAOB (0.38) | TBXAS1MAOBHDAC8KMT2AMEN1 | |
| SCHEMBL28347942 | 0.76 | MAOB (0.49) | MAOBKMT2AMEN1CYP1A2USP2 | |
| SCHEMBL28410857 | 0.76 | MAOB (0.50) | MAOBKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL28413016 | 0.76 | MAOB (0.49) | MAOBKMT2AMEN1CYP1A2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019036607-A1 | IMIDAZOLE-BASED ANTICANCER AGENTS AND DERIVATIVES THEREOF, AND METHODS OF MAKING AND USING SAME | THE UNIVERSITY OF TOLEDO (US) | 2019-02-21 | — | — | WO | disclosed |