Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM2 | O94759 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | POLQ | O75417 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26437709 | 0.89 | TRPM2 (0.40) | TRPM2LMNATSHRNPSR1POLB | |
| SCHEMBL14555812 | 0.82 | TRPM2 (0.44) | TRPM2LMNATSHRNPSR1POLB | |
| SCHEMBL15724335 | 0.81 | TRPM2 (0.47) | TRPM2LMNATSHRNPSR1POLB | |
| SCHEMBL31648679 | 0.76 | POLQ (0.43) | TRPM2TSHRPOLBCYP2C19CYP2C9 | |
| SCHEMBL15708370 | 0.76 | TRPM2 (0.41) | TRPM2LMNATSHRNPSR1POLB | |
| SCHEMBL21420050 | 0.75 | POLB (0.38) | TRPM2TSHRPOLBGAACYP2C19 | |
| SCHEMBL21420079 | 0.75 | POLB (0.38) | TRPM2TSHRPOLBGAACYP2C19 | |
| SCHEMBL21420046 | 0.75 | POLB (0.40) | TRPM2TSHRPOLBGAACYP2C19 | |
| SCHEMBL26251001 | 0.75 | POLB (0.40) | TRPM2TSHRPOLBGAACYP2C19 | |
| SCHEMBL14487702 | 0.75 | POLB (0.40) | TRPM2TSHRPOLBGAACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3668860-B1 | CHOLINE SALT FORMS OF AN HIV CAPSID INHIBITOR | GILEAD SCIENCES INC (US) | 2022-01-05 | — | — | EP | disclosed |
| WO-2019035973-A1 | CHOLINE SALT FORMS OF AN HIV CAPSID INHIBITOR | GILEAD SCIENCES, INC (US) | 2019-02-21 | — | — | WO | disclosed |