Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 4/20 | 0.43 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31648774 | 0.91 | POLQ (0.38) | POLQTRPM2PTGS2MAPK1HSD17B10 | |
| SCHEMBL31648550 | 0.87 | TRPM2 (0.42) | POLQTRPM2PTGS2MAPK1HSD17B10 | |
| SCHEMBL31648461 | 0.84 | POLQ (0.47) | POLQALDH1A1HTTTSHR | |
| SCHEMBL31648301 | 0.84 | MAPK1 (0.41) | TRPM2MAPK1HSD17B10POLBKDM4E | |
| SCHEMBL31648799 | 0.80 | PTGS2 (0.41) | POLQTRPM2PTGS2MAPK1HSD17B10 | |
| Hydrochloric Acid SCHEMBL31648923 | 0.79 | TRPM2 (0.37) | POLQTRPM2PTGS2MAPK1HSD17B10 | |
| SCHEMBL31648715 | 0.79 | PTGS2 (0.40) | POLQTRPM2PTGS2MAPK1HSD17B10 | |
| SCHEMBL14487510 | 0.78 | PTGS2 (0.40) | POLQTRPM2PTGS2MAPK1HSD17B10 | |
| SCHEMBL14484403 | 0.78 | POLQ (0.58) | POLQTRPM2PTGS2MAPK1HSD17B10 | |
| SCHEMBL14488499 | 0.77 | PTGS2 (0.43) | POLQTRPM2PTGS2MAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132946-A1 | PHENYLPYRROLIDINE DERIVATIVES AND THEIR USE AS POI-THETA DERIVATIVES | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |