Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19175930 | 0.89 | TSHR (0.32) | TSHRCYP1A2MAPK1 | |
| SCHEMBL20756264 | 0.87 | TSHR (0.40) | TSHRCYP1A2MAPK1 | |
| SCHEMBL14621520 | 0.86 | TSHR (0.40) | TSHRCYP1A2MAPK1 | |
| SCHEMBL23252530 | 0.85 | OPRM1 (0.41) | TSHRLMNA | |
| SCHEMBL21344517 | 0.82 | KDM4E (0.32) | — | |
| SCHEMBL15211775 | 0.80 | LMNA (0.56) | TSHRLMNA | |
| SCHEMBL13067946 | 0.76 | TSHR (0.40) | TSHRLMNA | |
| Water SCHEMBL9684502 | 0.75 | LMNA (0.44) | TSHRCYP1A2MAPK1LMNA | |
| SCHEMBL26318533 | 0.75 | TSHR (0.39) | TSHRCYP1A2MAPK1LMNA | |
| SCHEMBL26317082 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190053492-A1 | SUBSTITUTED PYRIDINE COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2019-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190053492-A1 | SUBSTITUTED PYRIDINE COMPOUNDS AS PESTICIDES | CHRM1, CHRM2, ACHE | TSHR 1420/4885CYP1A2 47/4885MAPK1 1178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.