Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20758934 | 0.94 | MAP3K14 (0.32) | MAP3K14 | |
| SCHEMBL21059025 | 0.87 | MAP3K14 (0.33) | MAP3K14 | |
| SCHEMBL10053970 | 0.84 | CCR5 (0.47) | CCR5MAP3K14 | |
| SCHEMBL25175873 | 0.82 | SLC6A1 (0.35) | MAP3K14 | |
| SCHEMBL7794999 | 0.80 | — | — | |
| SCHEMBL797262 | 0.78 | MAP3K14 (0.33) | MAP3K14 | |
| SCHEMBL797263 | 0.77 | MAP3K14 (0.39) | MAP3K14 | |
| SCHEMBL26984265 | 0.77 | — | — | |
| SCHEMBL20343542 | 0.76 | MAP3K14 (0.34) | MAP3K14 | |
| SCHEMBL11206101 | 0.76 | MAPT (0.38) | MAP3K14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210128555-A1 | CDK4/6 INHIBITORS AND USE THEREOF | BEIJING XUANYI PHARMASCIENCES CO., LTD. (CN) | 2021-05-06 | — | — | US | disclosed |
| WO-2019035008-A1 | CDK4/6 INHIBITORS AND USE THEREOF | BEIJING XUANYI PHARMASCIENCES CO., LTD. (CN) | 2019-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210128555-A1 | CDK4/6 INHIBITORS AND USE THEREOF | CDK4, CDK6, CDK1 | CCR5 3575/4885MAP3K14 260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.