SCHEMBL20759134

SCHEMBL20759134

C=C(CC)c1ccn(C(C)C)n1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 1/20 0.33
KDM5A P29375 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28111818 0.79 KDM5A (0.35) DYRK1AKDM5A
SCHEMBL25859547 0.78 ADORA3 (0.34) DYRK1A
SCHEMBL25859549 0.78 DYRK1A (0.35) DYRK1AKDM5A
SCHEMBL25859581 0.75 DYRK1A (0.33) DYRK1AKDM5A
SCHEMBL25332845 0.74 MEN1 (0.41) DYRK1AKDM5A
SCHEMBL10026473 0.72 MME (0.39) DYRK1AKDM5A
SCHEMBL25859551 0.71 MEN1 (0.39) DYRK1AKDM5A
SCHEMBL21756285 0.70 GSK3B (0.35) DYRK1AKDM5A
SCHEMBL12986040 0.69 MAPT (0.43)
SCHEMBL9974274 0.69 DYRK1A (0.39) DYRK1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019036657-A1 AHR INHIBITORS AND USES THEREOF KYN THERAPEUTICS (US) 2019-02-21 WO disclosed