Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21756285 | 0.84 | GSK3B (0.35) | KDM5AKMT2AMEN1HPGDMIF | |
| SCHEMBL25660359 | 0.82 | ALDH1A1 (0.32) | RIPK1KMT2AMEN1HPGDMIF | |
| SCHEMBL10026473 | 0.79 | MME (0.39) | KDM5AKMT2AMEN1HPGDDYRK1A | |
| SCHEMBL17065274 | 0.79 | KDM5A (0.37) | KDM5AKMT2AMEN1HPGDMIF | |
| SCHEMBL20759134 | 0.79 | DYRK1A (0.33) | KDM5ADYRK1A | |
| SCHEMBL1058997 | 0.78 | CYP1A2 (0.49) | HPGDLMNAALDH1A1TSHRMAPT | |
| SCHEMBL25332845 | 0.78 | MEN1 (0.41) | KDM5AKMT2AMEN1HPGDMIF | |
| SCHEMBL2810761 | 0.78 | ADORA2A (0.40) | KDM5AKMT2AMEN1HPGDDYRK1A | |
| SCHEMBL12535851 | 0.76 | TSHR (0.51) | KMT2AMEN1HPGDLMNAALDH1A1 | |
| SCHEMBL1431340 | 0.75 | KMT2A (0.44) | KDM5AKMT2AMEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106068265-A | Dihydropyridone MGAT2 inhibitors for the treatment of metabolic disorders | 百时美施贵宝公司 | 2016-11-02 | — | — | CN | disclosed |