Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | VNN1 | O95497 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL62132 | 0.86 | VNN1 (0.58) | KMT2AVNN1POLB | |
| SCHEMBL91172 | 0.86 | VNN1 (0.58) | KMT2AVNN1POLB | |
| SCHEMBL62325 | 0.84 | EPHX2 (0.72) | EPHX2MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL14548305 | 0.79 | ADRB2 (0.51) | KMT2ACYP3A4LMNAVNN1POLB | |
| Niacin SCHEMBL810843 | 0.78 | VNN1 (0.53) | KMT2AMEN1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL15592358 | 0.74 | KMT2A (0.58) | EPHX2MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10875319 | 0.74 | VNN1 (0.62) | EPHX2KMT2AMEN1CYP3A4ALDH1A1 | |
| Niacin SCHEMBL812051 | 0.73 | VNN1 (0.51) | MAPTKMT2AMEN1RAB9AALDH1A1 | |
| SCHEMBL4182430 | 0.73 | EPHX2 (1.00) | EPHX2MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9011202 | 0.72 | EPHX2 (0.67) | EPHX2KMT2AMEN1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7906496-B2 | Carboxylic acid derivatives | DSM IP ASSETS B.V. (NL) | 2011-03-15 | — | — | US | disclosed |
| EP-1926703-A1 | NOVEL CARBOXYLIC ACID DERIVATIVES | DSM IP Assets B.V. (NL) | 2008-06-04 | — | — | EP | disclosed |
| WO-2007039059-A1 | NOVEL CARBOXYLIC ACID DERIVATIVES | DSM IP ASSETS B.V. (NL) | 2007-04-12 | — | — | WO | disclosed |