Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20762480 | 0.86 | NPSR1 (0.47) | NPSR1KDM4ELMNAHTTMEN1 | |
| SCHEMBL20761833 | 0.85 | AGTR1 (0.54) | NPSR1KDM4ELMNAHTTMEN1 | |
| SCHEMBL20761851 | 0.84 | DRD2 (0.53) | NPSR1KDM4ELMNAHTTMEN1 | |
| SCHEMBL20762556 | 0.77 | KDM4C (0.52) | CTSDL3MBTL1 | |
| SCHEMBL13834603 | 0.76 | KMT2A (0.55) | NPSR1KDM4ELMNAHTTMEN1 | |
| SCHEMBL20761884 | 0.75 | AGTR1 (0.56) | NPSR1KDM4ELMNAHTTCTSD | |
| SCHEMBL20761785 | 0.74 | CTSD (0.50) | NPSR1KDM4ELMNAHTTMEN1 | |
| SCHEMBL20761957 | 0.72 | CTSD (0.49) | NPSR1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL19278312 | 0.72 | MAPT (0.50) | NPSR1KDM4ELMNAHTTMEN1 | |
| SCHEMBL20761651 | 0.71 | MC4R (0.45) | HTTGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190055212-A1 | HISTONE DEMETHYLASE INHIBITORS | GWALTNEY STEPHEN (US) | 2019-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190055212-A1 | HISTONE DEMETHYLASE INHIBITORS | KDM1B, KDM6B, KDM5B | NPSR1 4426/4885KDM4E 12/4885LMNA 2608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.