Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 3/20 | 0.33 |
| ▸ | RXRB | P28702 | 3/20 | 0.33 |
| ▸ | RXRG | P48443 | 3/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.33 |
| ▸ | SHBG | P04278 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 2/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20762859 | 0.83 | ESR1 (0.48) | KIF11KDM4EALDH1A1SLC13A5RXRA | |
| SCHEMBL20762688 | 0.73 | KIF11 (0.36) | KIF11ALDH1A1SLC13A5RXRARXRB | |
| SCHEMBL17427334 | 0.72 | KDM4E (0.38) | KDM4ECASP6ALDH1A1HPGDHSD17B10 | |
| SCHEMBL19738378 | 0.68 | FFAR1 (0.41) | KDM4EALDH1A1HPGDHSD17B10PTGS1 | |
| SCHEMBL17577153 | 0.68 | SHBG (0.42) | KDM4EALDH1A1HPGDHSD17B10SHBG | |
| SCHEMBL6059772 | 0.67 | KIF11 (0.50) | KIF11RXRARXRBRXRGHSD17B1 | |
| SCHEMBL17578343 | 0.67 | TP53 (0.44) | KDM4EALDH1A1HPGDHSD17B10PTGS1 | |
| SCHEMBL17058715 | 0.66 | CA1 (0.42) | KIF11KDM4EHSD17B1HSD17B2SHBG | |
| SCHEMBL17427311 | 0.66 | PDK2 (0.36) | KDM4ECASP6ALDH1A1HPGDHSD17B10 | |
| SCHEMBL17427322 | 0.66 | PDK2 (0.36) | KDM4ECASP6ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190056676-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, AND ELECTROPHOTOGRAPHIC APPARATUS AND PROCESS CARTRIDGE EACH INCLUDING THE ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | CANON KABUSHIKI KAISHA (JP) | 2019-02-21 | — | — | US | disclosed |