Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20762859 | 0.79 | ESR1 (0.48) | KIF11ALDH1A1SLC13A5RXRARXRB | |
| SCHEMBL1647493 | 0.73 | ALDH1A1 (0.65) | ALDH1A1MAOBPOLBTSHR | |
| SCHEMBL50012 | 0.73 | ALDH1A1 (0.65) | ALDH1A1MAOBPOLBTSHR | |
| SCHEMBL20762690 | 0.73 | KIF11 (0.41) | KIF11ALDH1A1SLC13A5MAOBRXRA | |
| SCHEMBL20762850 | 0.72 | TSHR (0.40) | KIF11ALDH1A1SLC13A5RXRARXRB | |
| SCHEMBL30309537 | 0.69 | AKR1C3 (0.42) | KIF11ALDH1A1AKR1C3AKR1C2HSD11B1 | |
| SCHEMBL7518860 | 0.69 | CA2 (0.46) | ALDH1A1GAATSHR | |
| SCHEMBL22317484 | 0.68 | ALDH1A1 (0.41) | ALDH1A1SLC13A5TSHR | |
| SCHEMBL1646806 | 0.66 | ALDH1A1 (0.48) | ALDH1A1MAOBTSHR | |
| SCHEMBL24355083 | 0.66 | ALDH1A1 (0.42) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190056676-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, AND ELECTROPHOTOGRAPHIC APPARATUS AND PROCESS CARTRIDGE EACH INCLUDING THE ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | CANON KABUSHIKI KAISHA (JP) | 2019-02-21 | — | — | US | disclosed |