Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL98490 | 0.96 | ALDH1A1 (0.47) | ALDH1A1KDM4EAPPCHRM2CHRM1 | |
| SCHEMBL1170638 | 0.94 | ALDH1A1 (0.42) | ALDH1A1KDM4EAPPCHRM2CHRM1 | |
| Water SCHEMBL29233228 | 0.94 | ALDH1A1 (0.45) | ALDH1A1KDM4EAPPCHRM2CHRM1 | |
| SCHEMBL9493022 | 0.94 | ALDH1A1 (0.45) | ALDH1A1KDM4EAPPCHRM2CHRM1 | |
| Water SCHEMBL15641777 | 0.92 | ALDH1A1 (0.44) | ALDH1A1KDM4EAPPCHRM2CHRM1 | |
| SCHEMBL2417 | 0.92 | ALDH1A1 (0.45) | ALDH1A1KDM4ECHRM2CHRM1KMT2A | |
| SCHEMBL2229127 | 0.92 | ALDH1A1 (0.45) | ALDH1A1KDM4ECHRM2CHRM1KMT2A | |
| SCHEMBL9790 | 0.92 | ALDH1A1 (0.45) | ALDH1A1KDM4ECHRM2CHRM1KMT2A | |
| SCHEMBL164218 | 0.92 | KDM4E (0.59) | ALDH1A1KDM4EHRH3SMN1; SMN2KMT2A | |
| SCHEMBL516054 | 0.92 | KDM4E (0.59) | ALDH1A1KDM4EHRH3SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088399-B2 | Ascorbic acid, ceramide precursor is 6-hydroxy-4-sphingenine base; cosmetic treatment of a subject whose lips are affected by chapping and/or cracks and/or bleeding associated with or not associated with scales and/or dry plaques and/or feeling of discomfort and/or tightness and/or smarting | L'OREAL (FR) | 2012-01-03 | — | — | US | disclosed |
| US-20110256192-A1 | PHOTOPROTECTIVE COMPOSITION CONTAINING AN UNMODIFIED GELLING STARCH AND POLYAMIDE PARTICLES | L'OREAL (FR) | 2011-10-20 | — | — | US | disclosed |
| EP-2370179-A1 | PHOTOPROTECTIVE COMPOSITION CONTAINING AN UNMODIFIED GELLING STARCH AND POLYAMIDE PARTICLES | L'Oréal (FR) | 2011-10-05 | — | — | EP | disclosed |
| US-20110027202-A1 | FLUID OIL-IN-WATER SUNSCREEN EMULSIONS CONTAINING GEMINI SURFACTANTS AND A CROSSLINKED COPOLYMER OF METHACRYLIC ACID AND OF C1-C4 ALKYL ACRYLATE | L'OREAL (FR) | 2011-02-03 | — | — | US | disclosed |
| US-20110015463-A1 | APPLICATOR AND A SET INCLUDING SUCH AN APPLICATOR | L'OREAL (FR) | 2011-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110027202-A1 | FLUID OIL-IN-WATER SUNSCREEN EMULSIONS CONTAINING GEMINI SURFACTANTS AND A CROSSLINKED COPOLYMER OF METHACRYLIC ACID AND OF C1-C4 ALKYL ACRYLATE | C1S, TP53, CDC25C | ALDH1A1 773/4885KDM4E 4867/4885APP 1683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.