Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL118027 | 0.96 | ALDH1A1 (0.45) | ALDH1A1KDM4ESMN1; SMN2APPCHRM2 | |
| SCHEMBL207631 | 0.94 | ALDH1A1 (0.44) | ALDH1A1KDM4ESMN1; SMN2APPCHRM2 | |
| SCHEMBL98490 | 0.90 | ALDH1A1 (0.47) | ALDH1A1KDM4ESMN1; SMN2APPCHRM2 | |
| SCHEMBL9790 | 0.90 | ALDH1A1 (0.45) | ALDH1A1KDM4ECHRM2CHRM1KMT2A | |
| SCHEMBL2229127 | 0.90 | ALDH1A1 (0.45) | ALDH1A1KDM4ECHRM2CHRM1KMT2A | |
| SCHEMBL2417 | 0.90 | ALDH1A1 (0.45) | ALDH1A1KDM4ECHRM2CHRM1KMT2A | |
| Water SCHEMBL29233228 | 0.89 | ALDH1A1 (0.45) | ALDH1A1KDM4ESMN1; SMN2APPCHRM2 | |
| SCHEMBL9493022 | 0.89 | ALDH1A1 (0.45) | ALDH1A1KDM4ESMN1; SMN2APPCHRM2 | |
| 1,4-Butanediol SCHEMBL7566107 | 0.89 | ALDH1A1 (0.41) | ALDH1A1KDM4ESMN1; SMN2APPCHRM2 | |
| SCHEMBL3653844 | 0.88 | ALDH1A1 (0.43) | ALDH1A1KDM4ECHRM2CHRM1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110166202-A1 | FORMOTEROL/STEROID BRONCHODILATING COMPOSITIONS AND METHODS OF USE THEREOF | DEY, L.P. (US) | 2011-07-07 | — | — | US | disclosed |
| US-20110135730-A1 | Oral Formulations of Glycyl-2-Methylprolyl-Glutamate | NEUREN PHARMACEUTICALS LIMITED (AU) | 2011-06-09 | — | — | US | disclosed |
| US-7887839-B2 | microemulsions, water in oil emulsion, continuous hydrophobic phase including oil, surfactant; for treatment of neurodegenerative disorders; tablets; pharmacokinetics, bioavailability | NEUREN PHARMACEUTICALS LTD. (NZ) | 2011-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166202-A1 | FORMOTEROL/STEROID BRONCHODILATING COMPOSITIONS AND METHODS OF USE THEREOF | ADRB2, CYP11B2, ADRB3 | ALDH1A1 2688/4885KDM4E 4789/4885SMN1; SMN2 1837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.