⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL10672402 | 0.97 | ALDH1A1 (0.33) | — | |
| SCHEMBL1457249 | 0.79 | ALDH1A1 (0.37) | — | |
| SCHEMBL9420651 | 0.78 | ALDH1A1 (0.32) | — | |
| SCHEMBL11052842 | 0.78 | — | — | |
| SCHEMBL12986645 | 0.74 | — | — | |
| Ethylene SCHEMBL9816770 | 0.74 | ALDH1A1 (0.33) | — | |
| SCHEMBL56546 | 0.74 | — | — | |
| SCHEMBL11749569 | 0.74 | ALDH1A1 (0.33) | — | |
| SCHEMBL5525771 | 0.74 | — | — | |
| SCHEMBL12987662 | 0.74 | DGAT1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116036282-B | Application of RNA helicase DHX33 inhibitor in preparation of medicine for treating prostate cancer | 深圳开悦生命科技有限公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-104001159-B | Lipid complex of a kind of insulin and preparation method thereof and preparation | 中国医学科学院药物研究所 | 2016-08-24 | — | — | CN | disclosed |
| US-20130116457-A1 | CLEAN, HIGH-YIELD PREPARATION OF S,S AND R,S AMINO ACID ISOSTERES | AEROJET FINE CHEMICALS LLC (US) | 2013-05-09 | — | — | US | disclosed |
| US-8163933-B2 | Clean, high-yield preparation of S,S and R,S amino acid isosteres | AMPAC FINE CHEMICALS LLC (US) | 2012-04-24 | — | — | US | disclosed |
| US-20090012303-A1 | CLEAN, HIGH-YIELD PREPARATION OF S,S AND R,S AMINO ACID ISOSTERES | AEROJET FINE CHEMICALS LLC (US) | 2009-01-08 | — | — | US | disclosed |
| US-7309803-B2 | Clean, High-yield preparation of S,S and R,S amino acid isosteres | AEROJET FINE CHEMICALS LLC (US) | 2007-12-18 | — | — | US | disclosed |
| US-20050171170-A1 | Clean, high-yield preparation of S,S and R,S amino acid isosteres | AEROJET FINE CHEMICALS LLC, A DELAWARE LIMITED LIABILITY COMPANY (US) | 2005-08-04 | — | — | US | disclosed |
| US-6867311-B2 | Clean, high-yield preparation of S,S and R,S amino acid isosteres | AEROJET FINE CHEMICALS LLC (US) | 2005-03-15 | — | — | US | disclosed |
| US-20030225292-A1 | Clean, high-yield preparation of S,S and R,S amino acid isosteres | AEROJET FINE CHEMICALS LLC, A DELAWARE LIMITED LIABILITY COMPANY | 2003-12-04 | — | — | US | disclosed |
| US-6605732-B1 | Clean, high-yield preparation of S,S and R,S amino acid isosteres | AEROJET FINE CHEMICALS LLC | 2003-08-12 | — | — | US | disclosed |
| EP-1050532-A2 | Preparation of S,S and R,S amino acid isosteres | Aerojet Fine Chemicals LLC (US) | 2000-11-08 | — | — | EP | disclosed |
| EP-0973746-A1 | SUBSTITUTED 3-CYANO QUINOLINES | American Cyanamid Company (US) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998043960-A1 | SUBSTITUTED 3-CYANO QUINOLINES | AMERICAN CYANAMID COMPANY (US) | 1998-10-08 | — | — | WO | disclosed |