Ethylene

Ethylene

SCHEMBL9816770

C=C.O=C(OCCOC(=O)C(Cl)(Cl)Cl)C(Cl)(Cl)Cl

nearest known ligand 0.33

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Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.33
TP53 P04637 3/20 0.33
TSHR P16473 3/20 0.33
HIF1A Q16665 2/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1457249 0.94 ALDH1A1 (0.37) ALDH1A1TP53TSHR
SCHEMBL7515879 0.84 ALDH1A1 (0.30) ALDH1A1TP53TSHR
SCHEMBL1457105 0.82 ALDH1A1 (0.48) ALDH1A1TSHRHSD17B10
SCHEMBL11341812 0.82 TSHR (0.41) ALDH1A1TSHR
SCHEMBL9420651 0.81 ALDH1A1 (0.32) ALDH1A1TP53TSHR
SCHEMBL11356672 0.81 ALDH1A1 (0.32) ALDH1A1TP53TSHR
SCHEMBL10072302 0.81 TSHR (0.41) ALDH1A1TP53TSHR
SCHEMBL6636802 0.80 ALDH1A1 (0.32) ALDH1A1TSHR
SCHEMBL8656281 0.80 THRB (0.55) ALDH1A1TSHR
SCHEMBL8746450 0.79 HCAR2 (0.40) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0135714-B1 SUSTAINED RELEASE COMPOSITIONS FOR BIOLOGICALLY ACTIVE MATERIALS MELAMINE CHEMICALS, INC. (US) 1991-11-06 EP disclosed
EP-0190996-A2 Crosslinked, porous polymers for controlled delivery of agricultural ingredients CIBA-GEIGY AG (CH) 1986-08-13 EP disclosed
US-4333759-A Herbicidal 5-cyano-2,3-dihydro-benzofuran-2-ones FISONS LIMITED (GB) 1982-06-08 US disclosed
US-4263037-A 5-Cyano-2,3-dihydrobenzofurans useful as herbicides FISONS LIMITED (GB) 1981-04-21 US disclosed
EP-0007719-A2 Cyanbenzofuran derivatives, processes for their preparation and their use in herbicidal compositions; cyanobenzene, benzodioxepine, benzodioxaphosphepine and benzodioxathiepine derivatives FBC LIMITED (GB) 1980-02-06 EP disclosed
US-4057643-A Antifungal compositions of butanediol bis (chloroacetate) CELANESE CORPORATION (US) 1977-11-08 US disclosed
US-4007258-A Sustained release pesticidal composition UNION CORPORATION (US) 1977-02-08 US disclosed
US-3940260-A TRICHLOROACETIC ACID, ESTERS OR SALTS AND 2,4-DICHLORO- OR 2,4,5-TRICHLORO- PHENOXYACETIC ACID, ESTERS OR SALTS AMCHEM PRODUCTS, INC. (US) 1976-02-24 US disclosed