Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20764686 | 0.86 | PNMT (0.49) | RXFP1ALDH1A1POLBAURKBNQO2 | |
| SCHEMBL20792613 | 0.85 | PPARG (0.47) | RXFP1FAAHCTSSCTSKNPSR1 | |
| SCHEMBL20792639 | 0.85 | SLC6A2 (0.48) | RXFP1SLC6A2SLC6A4ALDH1A1POLB | |
| SCHEMBL20792282 | 0.84 | FAAH (0.42) | RXFP1ALDH1A1POLBFAAHCTSS | |
| SCHEMBL27791751 | 0.83 | IDO1 (0.50) | ALDH1A1CTSSCTSKNPSR1MEN1 | |
| SCHEMBL20743103 | 0.81 | RXFP1 (0.41) | RXFP1SLC6A2SLC6A4AURKBNQO2 | |
| SCHEMBL20764632 | 0.81 | RXFP1 (0.40) | RXFP1ALDH1A1POLBAURKBNQO2 | |
| SCHEMBL10217145 | 0.80 | FAAH (0.46) | RXFP1ALDH1A1POLBFAAHCTSS | |
| SCHEMBL28429974 | 0.80 | FAAH (0.42) | RXFP1ALDH1A1POLBFAAHCTSS | |
| SCHEMBL22321391 | 0.80 | KCNQ3 (0.50) | RXFP1ALDH1A1POLBFAAHCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3672953-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL AS POTASSIUM CHANNEL INHIBITORS | Acesion Pharma ApS (DK) | 2020-07-01 | — | — | EP | disclosed |
| WO-2019038315-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL AS POTASSIUM CHANNEL INHIBITORS | ACESION PHARMA APS (DK) | 2019-02-28 | — | — | WO | disclosed |