SCHEMBL20765374

SCHEMBL20765374

Cc1nccc(Nc2cc(-c3cc(-c4ccccc4C(F)(F)F)[nH]c(=O)c3)ccn2)n1

nearest known ligand 0.77

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PIK3C3 Q8NEB9 19/20 0.77
NPY5R Q15761 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29701003 1.00 PIK3C3 (0.77) PIK3C3NPY5R
SCHEMBL29700993 0.88 PIK3C3 (0.60) PIK3C3
SCHEMBL22655427 0.88 PIK3C3 (0.60) PIK3C3
SCHEMBL20765429 0.87 PIK3C3 (1.00) PIK3C3NPY5R
SCHEMBL20765764 0.85 PIK3C3 (0.63) PIK3C3
SCHEMBL29700996 0.85 PIK3C3 (0.63) PIK3C3
SCHEMBL29701008 0.85 PIK3C3 (0.63) PIK3C3
SCHEMBL29700998 0.85 PIK3C3 (0.63) PIK3C3
SCHEMBL29035847 0.85 PIK3C3 (0.71) PIK3C3NPY5R
SCHEMBL20765433 0.83 PIK3C3 (1.00) PIK3C3NPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4169581-A1 PYRIDINAMINE-PYRIDONE AND PYRIMIDINAMINE-PYRIDONE COMPOUNDS Sprint Bioscience AB (SE) 2023-04-26 EP claimed
CN-111094271-B Pyridinamine-pyridinone compounds and pyrimidinamine-pyridinone compounds 思普瑞特生物科学公司 2023-02-28 CN claimed
US-20220177495-A1 PYRIDINAMINE-PYRIDONE AND PYRIMIDINAMINE-PYRIDONE COMPOUNDS SPRINT BIOSCIENCE AB (SE) 2022-06-09 US claimed
CN-111094271-A Pyridinamine-pyridinone compounds and pyrimidinamine-pyridinone compounds 思普瑞特生物科学公司 2020-05-01 CN claimed
WO-2020008046-A1 BIOMARKER SPRINT BIOSCIENCE AB (SE) 2020-01-09 WO claimed
US-11780858-B2 Pyridinamine-pyridone and pyrimidinamine-pyridone compounds SPRINT BIOSCIENCE AB (SE) 2023-10-10 US disclosed
US-11780858-B2 Pyridinamine-pyridone and pyrimidinamine-pyridone compounds SPRINT BIOSCIENCE AB (SE) 2023-10-10 US disclosed
US-11780858-B2 Pyridinamine-pyridone and pyrimidinamine-pyridone compounds SPRINT BIOSCIENCE AB (SE) 2023-10-10 US disclosed
EP-4169581-A1 PYRIDINAMINE-PYRIDONE AND PYRIMIDINAMINE-PYRIDONE COMPOUNDS Sprint Bioscience AB (SE) 2023-04-26 EP disclosed
CN-111094271-B Pyridinamine-pyridinone compounds and pyrimidinamine-pyridinone compounds 思普瑞特生物科学公司 2023-02-28 CN disclosed
EP-3672948-B1 PYRIDINAMINE-PYRIDONE AND PYRIMIDINAMINE-PYRIDONE COMPOUNDS SPRINT BIOSCIENCE AB (SE) 2022-10-05 EP disclosed
US-20220177495-A1 PYRIDINAMINE-PYRIDONE AND PYRIMIDINAMINE-PYRIDONE COMPOUNDS SPRINT BIOSCIENCE AB (SE) 2022-06-09 US disclosed
US-11208423-B2 Pyridinamine-pyridone and pyrimidinamine- pyridone compounds SPRINT BIOSCIENCE AB (SE) 2021-12-28 US disclosed
US-11208423-B2 Pyridinamine-pyridone and pyrimidinamine- pyridone compounds SPRINT BIOSCIENCE AB (SE) 2021-12-28 US disclosed
US-20200361963-A1 PYRIDINAMINE-PYRIDONE AND PYRIMIDINAMINE-PYRIDONE COMPOUNDS SPRINT BIOSCIENCE AB (SE) 2020-11-19 US disclosed
US-20200361963-A1 PYRIDINAMINE-PYRIDONE AND PYRIMIDINAMINE-PYRIDONE COMPOUNDS SPRINT BIOSCIENCE AB (SE) 2020-11-19 US disclosed
EP-3672948-A1 PYRIDINAMINE-PYRIDONE AND PYRIMIDINAMINE-PYRIDONE COMPOUNDS Sprint Bioscience AB (SE) 2020-07-01 EP disclosed
CN-111094271-A Pyridinamine-pyridinone compounds and pyrimidinamine-pyridinone compounds 思普瑞特生物科学公司 2020-05-01 CN disclosed
WO-2020008046-A1 BIOMARKER SPRINT BIOSCIENCE AB (SE) 2020-01-09 WO disclosed
WO-2019038389-A1 PYRIDINAMINE-PYRIDONE AND PYRIMIDINAMINE-PYRIDONE COMPOUNDS SPRINT BIOSCIENCE AB (SE) 2019-02-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11780858-B2 Pyridinamine-pyridone and pyrimidinamine-pyridone compounds PDXK, PLPBP, PNPO PIK3C3 3787/4885NPY5R 122/4885
US-11208423-B2 Pyridinamine-pyridone and pyrimidinamine- pyridone compounds PDXK, PLPBP, PNPO PIK3C3 3838/4885NPY5R 134/4885
US-20220177495-A1 PYRIDINAMINE-PYRIDONE AND PYRIMIDINAMINE-PYRIDONE COMPOUNDS PDXK, PLPBP, PNPO PIK3C3 3787/4885NPY5R 122/4885
US-20200361963-A1 PYRIDINAMINE-PYRIDONE AND PYRIMIDINAMINE-PYRIDONE COMPOUNDS PDXK, PLPBP, PNPO PIK3C3 3838/4885NPY5R 134/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.