Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 7/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | DRD3 | P35462 | 7/20 | 0.60 |
| ▸ | DRD2 | P14416 | 6/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20765703 | 0.84 | DRD3 (0.71) | KCNA5MEN1KMT2ADRD3DRD2 | |
| SCHEMBL20765543 | 0.79 | SMN1; SMN2 (0.79) | MEN1KMT2AL3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL12431599 | 0.78 | SMN1; SMN2 (0.70) | MEN1KMT2AL3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL20765557 | 0.78 | L3MBTL1 (0.58) | MEN1KMT2AL3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL12431600 | 0.77 | ALDH1A1 (0.71) | MEN1KMT2AL3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL20765535 | 0.77 | KDM4E (0.57) | MEN1KMT2AL3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL11071009 | 0.76 | DRD3 (0.66) | KCNA5MEN1KMT2ADRD3DRD2 | |
| SCHEMBL16598822 | 0.76 | KDM4E (0.59) | MEN1KMT2AL3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL20765504 | 0.76 | ALDH1A1 (0.64) | MEN1KMT2AL3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL5805385 | 0.76 | ALDH1A1 (0.70) | MEN1KMT2AL3MBTL1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019038683-A1 | COMPOUNDS TARGETING TANDEM BRCT DOMAINS OF BRCA1, COMPOSITIONS AND METHODS THEREOF | INSTITUTE FOR STEM CELL BIOLOGY AND REGENERATIVE MEDICINE (IN) | 2019-02-28 | — | — | WO | claimed |