Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.48 |
| ▸ | BACE1 | P56817 | 3/20 | 0.48 |
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20766113 | 1.00 | ACHE (0.48) | ACHEBACE1BCHESIGMAR1TMEM97 | |
| SCHEMBL20794528 | 0.87 | ACHE (0.48) | ACHEBACE1BCHE | |
| SCHEMBL20794530 | 0.87 | ACHE (0.48) | ACHEBACE1BCHE | |
| SCHEMBL25124475 | 0.76 | HTR5A (0.37) | TACR1KCNH2 | |
| SCHEMBL20794790 | 0.74 | BCHE (0.48) | ACHEBACE1BCHESIGMAR1TMEM97 | |
| SCHEMBL20767467 | 0.74 | BCHE (0.48) | ACHEBACE1BCHESIGMAR1TMEM97 | |
| SCHEMBL29558081 | 0.71 | ADRA1A (0.38) | TACR1KCNH2 | |
| SCHEMBL17207645 | 0.71 | ADRA1A (0.38) | TACR1KCNH2 | |
| SCHEMBL970899 | 0.70 | ACHE (0.62) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL1239998 | 0.70 | BCHE (0.61) | ACHEBACE1BCHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019040106-A2 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | ACADIA PHARMACEUTICALS INC. (US) | 2019-02-28 | — | — | WO | disclosed |
| WO-2019040106-A2 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | ACADIA PHARMACEUTICALS INC. (US) | 2019-02-28 | — | — | WO | disclosed |