Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 12/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24424530 | 0.77 | NCF1 (0.34) | CYP19A1CYP11B1CYP11B2KCNH2 | |
| SCHEMBL23623038 | 0.73 | IDO1 (0.33) | CYP19A1CYP11B1CYP11B2KCNH2 | |
| SCHEMBL24928597 | 0.73 | CYP19A1 (0.35) | CYP19A1CYP11B1CYP11B2KCNH2 | |
| SCHEMBL20225483 | 0.69 | MAPT (0.32) | — | |
| SCHEMBL18365858 | 0.68 | SSTR2 (0.31) | SSTR2 | |
| Hydrochloric Acid SCHEMBL25303729 | 0.67 | CYP17A1 (0.37) | — | |
| SCHEMBL2355428 | 0.66 | CYP19A1 (0.54) | CYP19A1CYP11B1CYP11B2KCNH2 | |
| SCHEMBL24424515 | 0.66 | ADH1B (0.38) | — | |
| SCHEMBL24035779 | 0.65 | DRD2 (0.50) | — | |
| SCHEMBL3933129 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019040106-A2 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | ACADIA PHARMACEUTICALS INC. (US) | 2019-02-28 | — | — | WO | disclosed |